VAC14 and SMUG1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VAC14	SMUG1
Gene Name		Vac14 homolog (S. cerevisiae)	single-strand-selective monofunctional uracil-DNA glycosylase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endosome Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex	Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	Receptor Activity Protein Binding	Oxidized Pyrimidine Nucleobase Lesion DNA N-glycosylase Activity DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Single-strand Selective Uracil DNA N-glycosylase Activity DNA N-glycosylase Activity
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Regulation Of Lipid Kinase Activity Small Molecule Metabolic Process	DNA Catabolic Process, Endonucleolytic DNA Repair Base-excision Repair Base-excision Repair, AP Site Formation Depyrimidination
Pathways		Phospholipid metabolism Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the late endosome membrane Metabolism Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the early endosome membrane PI Metabolism Phospholipid metabolism PI Metabolism	Base Excision Repair Depyrimidination Resolution of AP sites via the multiple-nucleotide patch replacement pathway Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected pyrimidine Removal of DNA patch containing abasic residue Base-Excision Repair, AP Site Formation Resolution of AP sites via the single-nucleotide replacement pathway Base-free sugar-phosphate removal via the single-nucleotide replacement pathway Displacement of DNA glycosylase by APE1 Resolution of Abasic Sites (AP sites)
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ACSS1 APP ASB13 BHLHE40 C11orf54 C4orf33 CASP1 CCBL1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 DDAH2 FIG4 FNDC3B JMJD7 KRTAP19-5 KRTAP19-7 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 TCEANC TP53BP1 WDYHV1 ZNF34	3 interactors: RBPMS TRIP13 VAC14
Entrez ID		55697	23583
HPRD ID		07660	06376
Ensembl ID		ENSG00000103043	ENSG00000123415
Uniprot IDs		Q08AM6 Q9NTB8	Q53HV7
PDB IDs
Enriched GO Terms of Interacting Partners?		Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Arginine Metabolic Process Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Nitric Oxide Metabolic Process Cellular Amino Acid Catabolic Process Cell Recognition Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Neuron Maturation Myelin Assembly Second-messenger-mediated Signaling Myelination Neuron Recognition Axon Ensheathment
Tagcloud ?		abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis	adjuvant anthracycline ape1 ar atm cdk1 chk2 cohorts consortium cyclophosphamide deregulation endocrine fen1 fluorouracil low lymphovascular methotrexate mib1 mitotic pkcs pleomorphism polbeta pr ps sporadic taxonomy topo2a worst xrcc1
Tagcloud (Difference) ?		abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis	adjuvant anthracycline ape1 ar atm cdk1 chk2 cohorts consortium cyclophosphamide deregulation endocrine fen1 fluorouracil low lymphovascular methotrexate mib1 mitotic pkcs pleomorphism polbeta pr ps sporadic taxonomy topo2a worst xrcc1
Tagcloud (Intersection) ?