VAC14 and CCBL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VAC14	CCBL1
Gene Name		Vac14 homolog (S. cerevisiae)	cysteine conjugate-beta lyase, cytoplasmic
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endosome Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Receptor Activity Protein Binding	Transaminase Activity Kynurenine-oxoglutarate Transaminase Activity Pyridoxal Phosphate Binding L-phenylalanine-oxaloacetate Transaminase Activity Protein Homodimerization Activity L-phenylalanine:pyruvate Aminotransferase Activity Glutamine-phenylpyruvate Transaminase Activity Cysteine-S-conjugate Beta-lyase Activity L-glutamine:pyruvate Aminotransferase Activity
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Regulation Of Lipid Kinase Activity Small Molecule Metabolic Process	L-phenylalanine Catabolic Process Tryptophan Catabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amino Acid Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Kynurenine Metabolic Process L-kynurenine Catabolic Process
Pathways		Phospholipid metabolism Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the late endosome membrane Metabolism Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the early endosome membrane PI Metabolism Phospholipid metabolism PI Metabolism	Phenylalanine and tyrosine catabolism Abnormal metabolism in phenylketonuria Amino acid synthesis and interconversion (transamination) Tryptophan catabolism Metabolism of amino acids and derivatives
Drugs			Pyridoxal Phosphate Pyridoxamine-5\'-Phosphate D-Phenylalanine N\'-Pyridoxyl-Lysine-5\'-Monophosphate 1H-INDOL-3-YLACETIC ACID
Diseases
GWAS
Protein-Protein Interactions		47 interactors: ACSS1 APP ASB13 BHLHE40 C11orf54 C4orf33 CASP1 CCBL1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 DDAH2 FIG4 FNDC3B JMJD7 KRTAP19-5 KRTAP19-7 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 TCEANC TP53BP1 WDYHV1 ZNF34	3 interactors: APP TRIP13 VAC14
Entrez ID		55697	883
HPRD ID		07660	02769
Ensembl ID		ENSG00000103043	ENSG00000171097
Uniprot IDs		Q08AM6 Q9NTB8	A8K563 B7Z4W5 Q16773
PDB IDs			1W7L 1W7M 1W7N 3FVS 3FVU 3FVX
Enriched GO Terms of Interacting Partners?		Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Arginine Metabolic Process Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Nitric Oxide Metabolic Process Cellular Amino Acid Catabolic Process Cell Recognition Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Neuron Maturation Myelin Assembly Second-messenger-mediated Signaling Myelination Neuron Recognition Axon Ensheathment	Cell Maturation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Female Meiosis I Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Synaptonemal Complex Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Synaptonemal Complex Organization Oocyte Maturation Regulation Of Kinase Activity Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Male Meiosis I Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Female Meiotic Division Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Reproduction Ionotropic Glutamate Receptor Signaling Pathway Reciprocal Meiotic Recombination Regulation Of G2/M Transition Of Mitotic Cell Cycle Oocyte Development Oocyte Differentiation Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Lipid Kinase Activity Synapsis Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Homologous Chromosome Segregation Regulation Of Protein Tyrosine Kinase Activity Male Meiosis Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death
Tagcloud ?		abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis
Tagcloud (Difference) ?		abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis
Tagcloud (Intersection) ?