RHOXF2 and NKX1-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHOXF2	NKX1-2
Description		Rhox homeobox family member 2	NK1 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleolus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Neuron Development	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Iron status biomarkers (ferritin levels) ( 28334935)
Interacting Genes		101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CIMIP2A CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683	2 interacting genes: PRR13 RHOXF2
Entrez ID		84528	390010
HPRD ID		02345
Ensembl ID		ENSG00000131721	ENSG00000229544
Uniprot IDs		Q9BQY4	Q9UD57
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Regulation Of MRNA Metabolic Process Poly(A) RNA Polymerase Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Stabilization Protein Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of RNA Splicing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability Regulation Of MRNA Processing Procollagen Galactosyltransferase Activity Transcription Factor Binding Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Nucleus Small Protein Activating Enzyme Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Anoikis Negative Regulation Of Metabolic Process RNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Anoikis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Stress Granule
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