RHOXF2 and DTX2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RHOXF2	DTX2
Gene Name		Rhox homeobox family, member 2	deltex 2, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Protein Binding Sequence-specific DNA Binding	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated	Notch Signaling Pathway Protein Ubiquitination
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		56 interactors: AES ARID5A ATN1 ATXN1 CCDC33 CCNK CHAC1 CLASRP CLDN7 CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM103A1 FAM46B FAM46C FAM46D FBF1 HNRNPLL HOXC13 KRTAP19-5 KRTAP19-7 LASP1 LENG8 LSM4 LZTS2 MAGED1 MED7 MVP NANOG NEU4 PITX1 PLOD3 POLR3D POU2AF1 PSMF1 RADIL RBFOX1 RBFOX2 RBM11 RBPMS SERF2 SNAPC1 SUMO1 TMCC2 TOLLIP TRIP13 UPF1 UTP6 VAC14 VPS25 ZBTB32	41 interactors: ABHD16A ALKBH4 ARNT2 C1orf94 DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS RBPMS RFX6 RHOXF2 RIMBP3 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1
Entrez ID		84528	113878
HPRD ID		02345	16841
Ensembl ID		ENSG00000131721	ENSG00000091073
Uniprot IDs		Q9BQY4	Q86UW9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Processing Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression MRNA Metabolic Process Cellular Metabolic Process MRNA Processing Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Radial Glia Guided Migration Of Purkinje Cell Anatomical Structure Development Regulation Of RNA Splicing Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Developmental Process Regulation Of Cellular Process Negative Regulation Of Gene Expression Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process RNA Splicing Negative Regulation Of Wnt Signaling Pathway Cellular Process Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Cell Migration In Hindbrain Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Signaling Positive Regulation Of Protein Modification Process	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Transcription From RNA Polymerase II Promoter Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Innate Immune Response Protein K11-linked Ubiquitination RNA Metabolic Process Cellular Response To Oxygen Levels Heart Trabecula Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Hypoxia Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Notch Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Pancreatic Epsilon Cell Differentiation Glutaminyl-tRNA Aminoacylation Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Pancreatic D Cell Differentiation Cleavage Furrow Ingression Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination Glandular Epithelial Cell Differentiation Signal Transduction Trabecula Morphogenesis Positive Regulation Of Innate Immune Response Vesicle Fusion Regulation Of Immune System Process Prolyl-tRNA Aminoacylation Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Histamine Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		ba carcinogenesis cdna cloning expresses f3 focused gadd45b gastric glioma hf6 hgc27 homeobox irradiated libraries lines oncogenes pim quickly render rendered repressor reproductive retrovirus searched sublethally transduced transplanted	algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Difference) ?		ba carcinogenesis cdna cloning expresses f3 focused gadd45b gastric glioma hf6 hgc27 homeobox irradiated libraries lines oncogenes pim quickly render rendered repressor reproductive retrovirus searched sublethally transduced transplanted	algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Intersection) ?