RHOXF2 and KLHDC7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHOXF2	KLHDC7B
Description		Rhox homeobox family member 2	kelch domain containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Neuron Development
Pathways
Drugs
Diseases
GWAS			Age-related hearing impairment ( 34108613) Mean corpuscular hemoglobin ( 20139978) Monocyte count ( 32888494) Red blood cell count ( 29403010) Serum metabolite levels ( 33031748)
Interacting Genes		101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CIMIP2A CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683	25 interacting genes: A1CF BHLHE40 CFTR DTX2 ESRP1 FNDC3B HNRNPUL1 LIMS3 LIMS4 MAPRE3 NFYC PATZ1 PHC2 POGZ QRICH1 RBPMS RBPMS2 RHOXF2 SMUG1 SPMIP9 TBX6 TLE5 TP53BP1 WWOX ZC3H10
Entrez ID		84528	113730
HPRD ID		02345	14453
Ensembl ID		ENSG00000131721	ENSG00000130487
Uniprot IDs		Q9BQY4	A0A3B3ISF6 Q96G42
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Regulation Of MRNA Metabolic Process Poly(A) RNA Polymerase Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Stabilization Protein Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of RNA Splicing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability Regulation Of MRNA Processing Procollagen Galactosyltransferase Activity Transcription Factor Binding Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Nucleus Small Protein Activating Enzyme Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Anoikis Negative Regulation Of Metabolic Process RNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Anoikis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Stress Granule	Nucleus Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding MRNA Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Single-strand Selective Uracil DNA N-glycosylase Activity Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Positive Regulation Of Metabolic Process
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