VAC14 and KRTAP19-3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VAC14	KRTAP19-3
Description		VAC14 component of PIKFYVE complex	keratin associated protein 19-3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Endoplasmic Reticulum Cytosol Endosome Membrane Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex Presynaptic Endosome	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Signaling Receptor Activity Identical Protein Binding	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Signal Transduction Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways		Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane	Keratinization
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Pulse pressure ( 28135244)
Interacting Genes		107 interacting genes: ABHD11 ACSS1 ACTMAP AMT APP ARID5A ASB13 ATM BCL2L1 BHLHE40 BKGD C4orf33 CASP1 CATSPERT CD209 CDRT4 CNTN2 COL8A1 CRK CRYBA1 CRYBA2 DDAH2 DNAAF19 EEF1AKMT3 EHHADH EIF2S1 EIF6 FAM50B FNDC3B GABPB2 GALT GINS3 GLIS2 GNB1 GTF3C2 HDHD3 HNF1B HNRNPLL INTS11 JMJD7 KHDC1 KRABD5 KRT82 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LINC00518 LPAL2 MBLAC1 MEOX2 METTL15 MGAT5B MPPED2 MTMR9 MVP MYOZ1 NDUFAB1 NGB NOS1 NTAQ1 OIT3 OTOS PBLD PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PPP6C PRADC1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX2 RHBDL1 RHOXF2 RIPPLY1 RNASEH2C RSKR SIGLEC5 SMUG1 SNF8 SPMIP9 SPRYD7 SRPK2 TCEANC TP53BP1 TRIM55 TRIM63 UFSP1 VENTX VHLL WDR83 WRAP53 ZBTB49 ZCWPW1 ZNF34	17 interacting genes: ARID5A BOLL CAMK2A CAMK2B CAMK2G CREB5 CYSRT1 DAZAP2 GLIS2 LASP1 NAF1 POU2AF1 RBPMS SMR3A TNIP1 UBQLN2 VAC14
Entrez ID		55697	337970
HPRD ID		07660	11207
Ensembl ID		ENSG00000103043	ENSG00000244025
Uniprot IDs		Q08AM6	Q7Z4W3
PDB IDs		7K1Y
Enriched GO Terms of Interacting Partners?		Protein Binding Intermediate Filament	Identical Protein Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Calcium/calmodulin-dependent Protein Kinase Activity Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Endocytic Vesicle Membrane Regulation Of Skeletal Muscle Adaptation Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Synaptic Transmission Positive Regulation Of Biosynthetic Process Regulation Of Protein Localization To Cell Periphery Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Localization To Membrane Sarcoplasmic Reticulum Membrane Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Synaptic Plasticity Peptidyl-threonine Autophosphorylation Regulation Of Neuron Migration Calmodulin Binding Positive Regulation Of RNA Metabolic Process Regulation Of RNA Stability PAS Complex Regulation Of Calcium Ion Transport Postsynaptic Density Regulation Of Biological Quality Negative Regulation Of G Protein-coupled Receptor Internalization Box H/ACA SnoRNP Assembly Regulation Of Primary Metabolic Process Sarcoplasmic Reticulum Regulation Of Receptor Internalization Transcription Coactivator Activity Regulation Of Endocannabinoid Signaling Pathway Calcium-dependent Protein Serine/threonine Phosphatase Activity RNA Stabilization SnoRNA Guided RRNA Pseudouridine Synthesis
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