MYBL2 and SND1

Number of citations of the paper that reports this interaction (PubMedID 11259168)
0

Data Source:
HPRD (in vitro)

		MYBL2	SND1
Description		MYB proto-oncogene like 2	staphylococcal nuclease and tudor domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Myb Complex	Nucleus Cytoplasm Cytosol Membrane RNAi Effector Complex Melanosome Extracellular Exosome Dense Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity Cadherin Binding RISC Complex Binding
	Biological Process	Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Mitotic Spindle Assembly Cellular Response To Leukemia Inhibitory Factor	Osteoblast Differentiation MRNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Regulatory NcRNA-mediated Gene Silencing
Pathways		Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Polo-like kinase mediated events TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Fasting insulin ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Haemorrhoidal disease ( 33888516) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 23532257 32499647)
Interacting Genes		29 interacting genes: CCNA1 CCNA2 CCND1 CCNE1 CCNF CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622	28 interacting genes: APP CEBPA CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 HOXA1 LINC00624 LZTR1 MAK MYB MYBL2 PDE4B PIM1 POLR2A PRPF8 PTGER4 RBPJ RNF10 RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I
Entrez ID		4605	27044
HPRD ID		03247	03714
Ensembl ID		ENSG00000101057	ENSG00000197157
Uniprot IDs		P10244	A0A140VK49 Q7KZF4
PDB IDs		6C48	2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O 7KNW 7KNX
Enriched GO Terms of Interacting Partners?		Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Cyclin A2-CDK2 Complex Nucleus Protein Modification Process Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleoplasm Post-translational Protein Modification Transcription Regulator Complex Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Microtubule Organizing Center Nucleic Acid Metabolic Process DNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Cyclin A1-CDK2 Complex Histone H3K27 Acetyltransferase Activity Negative Regulation Of DNA-templated Transcription Transcription Repressor Complex Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle DNA-templated Transcription Macromolecule Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Kinase Binding Cyclin E1-CDK2 Complex Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Nucleobase-containing Compound Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Transcription By RNA Polymerase II Re-entry Into Mitotic Cell Cycle Regulation Of Nucleobase-containing Compound Metabolic Process Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Androgen Receptor Signaling Pathway Transcription Pausing By RNA Polymerase II Negative Regulation Of Fat Cell Proliferation Regulation Of RNA Metabolic Process DNA Damage Response Regulation Of Metabolic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination RNA Metabolic Process	Formation Of Quadruple SL/U4/U5/U6 SnRNP Spliceosomal Tri-snRNP Complex Assembly Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process U4/U6 X U5 Tri-snRNP Complex Spliceosomal SnRNP Assembly Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Factor TFIIE Complex Positive Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Cellular Component Assembly Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Transcription Coactivator Binding Nucleoplasm Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Cell Activation Involved In Immune Response U6 SnRNA Binding Response To Cytokine Response To Peptide Protein-containing Complex Organization DNA Binding Regulation Of MiRNA Transcription Mammary Gland Epithelial Cell Proliferation Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Protein Catabolic Process Regulation Of Stem Cell Proliferation Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of MiRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Transcription Factor Binding SUMO Transferase Activity U5 SnRNP Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Cellular Response To Cytokine Stimulus
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