MYBL2 and CDC34

Number of citations of the paper that reports this interaction (PMID 10871850)
20

Data Source:
HPRD (in vivo)

		MYBL2	CDC34
Gene Name		v-myb avian myeloblastosis viral oncogene homolog-like 2	cell division cycle 34
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Myb Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Mitotic Spindle Assembly	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination DNA Replication Initiation Cellular Protein Modification Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Response To Growth Factor Protein K48-linked Ubiquitination Positive Regulation Of Inclusion Body Assembly
Pathways		G2/M Transition G0 and Early G1 Mitotic G2-G2/M phases Mitotic G1-G1/S phases Polo-like kinase mediated events Cell Cycle, Mitotic	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CCNA1 CCNA2 CCND1 CCNE1 CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622	45 interactors: ANAPC11 ATF5 BTRC CCNE1 CDK9 CDKN1B CREM CSNK2B CUL1 CUL2 CUL3 FBXL2 FBXL3 FBXO32 FBXO4 FBXO7 FBXW2 FBXW7 HIF1A ING4 ITCH MARCH1 MARCH2 MYBL2 MYOD1 NEDD4L NEDD8 NFKBIA PPARG RBX1 RELA RNF7 ROCK1 SDCBP SIAH1 SKP2 TBL1X TRIM21 TRIM28 UBA1 UBB VHL WWP2 ZFAND6 ZNRF1
Entrez ID		4605	997
HPRD ID		03247	00306
Ensembl ID		ENSG00000101057	ENSG00000099804
Uniprot IDs		B7Z8D9 F8W6N6 P10244	P49427
PDB IDs			2OB4 3RZ3
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Notch Signaling Pathway Cell Cycle G1/S Transition Of Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cell Cycle Cell Cycle Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Phase Transition Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Response To Stress RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process	Protein Modification By Small Protein Conjugation Protein Ubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Proteolysis Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Viral Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Protein Monoubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Catabolic Process Mitotic Cell Cycle Phase Transition Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Gene Expression Cell Cycle Phase Transition Cellular Response To Oxygen Levels Cellular Response To Stimulus Regulation Of Protein Catabolic Process Response To Stimulus Cellular Response To Stress Regulation Of Protein Stability Notch Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Cycle Negative Regulation Of RNA Biosynthetic Process Cell Cycle Regulation Of Transcription, DNA-templated Apoptotic Process Regulation Of Nucleic Acid-templated Transcription G1/S Transition Of Mitotic Cell Cycle Regulation Of RNA Biosynthetic Process Programmed Cell Death Regulation Of Protein Metabolic Process
Tagcloud ?		12q 12q21 14q31 15q25 16q23 18p 19q13 20p12 20pq 20q12 21q21 3p14 4pq 5p14 5q14 6p12 7p12 8q23 cardia cdkn2 fist gej mlvi2 mts1 nrasl3 parentheses ptpn1 rca1 xpq xq25	apparatus assemble associates box cdk cdk2 cerevisiae clock conjugating conjugation cul cullin dependency e3 facilitates governed imply ligase multiprotein p19 p45 periodic saccharomyces scf scfcdc4 skp1 skp2 tight ubiquitin
Tagcloud (Difference) ?		12q 12q21 14q31 15q25 16q23 18p 19q13 20p12 20pq 20q12 21q21 3p14 4pq 5p14 5q14 6p12 7p12 8q23 cardia cdkn2 fist gej mlvi2 mts1 nrasl3 parentheses ptpn1 rca1 xpq xq25	apparatus assemble associates box cdk cdk2 cerevisiae clock conjugating conjugation cul cullin dependency e3 facilitates governed imply ligase multiprotein p19 p45 periodic saccharomyces scf scfcdc4 skp1 skp2 tight ubiquitin
Tagcloud (Intersection) ?