CLTA

Description		clathrin light chain A
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Spindle Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Membrane Clathrin Coat Clathrin Vesicle Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Endolysosome Membrane Clathrin-coated Endocytic Vesicle Clathrin Complex Presynaptic Endocytic Zone Membrane Postsynaptic Endocytic Zone
	Molecular Function	Structural Molecule Activity Protein Binding Clathrin Heavy Chain Binding Peptide Binding Protein-containing Complex Binding GTPase Binding
	Biological Process	Intracellular Protein Transport Endocytosis Vesicle-mediated Transport Clathrin Coat Assembly Synaptic Vesicle Endocytosis Cell Division Clathrin-dependent Endocytosis
Pathways		Entry of Influenza Virion into Host Cell via Endocytosis Retrograde neurotrophin signalling Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Lysosome Vesicle Biogenesis Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172) Bisphosphonate-associated atypical femoral fracture ( 31006051)
Novel Interacting Genes		1 novel interacting genes: IFT57
Interacting Genes		10 interacting genes: CEBPA CLTC EGFR HIP1 HIP1R HSPA8 MAP1LC3B RGS2 SHANK3 SYNJ1
Entrez ID		1211
HPRD ID		00351
Ensembl ID		ENSG00000122705
Uniprot IDs		C9J8P9 P09496
PDB IDs		6E5N
Enriched GO Terms of Interacting Partners?		Vesicle Uncoating Clathrin Coat Disassembly Clathrin Light Chain Binding Clathrin Coat Assembly Protein-containing Complex Disassembly Protein Depolymerization Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Clathrin Coat Of Coated Pit Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of ERBB Signaling Pathway Clathrin-coated Vesicle Learning Or Memory Regulation Of Cellular Component Organization Cognition Clathrin Adaptor Activity Phospholipid Binding Protein-containing Complex Organization Embryonic Placenta Development Endocytosis Phosphatidylinositol-3,4-bisphosphate Binding Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Supramolecular Fiber Organization Phosphatidylinositol-3,5-bisphosphate Binding Brown Fat Cell Differentiation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Component Assembly Positive Regulation Of ERBB Signaling Pathway Clathrin-coated Vesicle Membrane Clathrin Binding Actin Filament Binding Postsynapse Organization Positive Regulation Of Cellular Component Organization Import Into Cell RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Multivesicular Body, Internal Vesicle Lumen Endomembrane System Cortical Actin Cytoskeleton Chaperone-mediated Autophagy Translocation Complex Disassembly Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Positive Regulation Of Endosome Organization Positive Regulation Of Clathrin Coat Assembly Autophagy Synaptic Membrane Cytosol Ubiquitin Protein Ligase Binding Cytoplasm Clathrin-coated Endocytic Vesicle Membrane Clathrin-coated Pit
Tagcloud ?