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FAM124B and ADAMTSL4
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
FAM124B
ADAMTSL4
Gene Name
family with sequence similarity 124B
ADAMTS-like 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Interstitial Matrix
Endoplasmic Reticulum Lumen
Molecular Function
Protein Binding
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Biological Process
Protein O-linked Glycosylation
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Protein O-linked Fucosylation
Positive Regulation Of Apoptotic Process
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Post-translational protein modification
O-glycosylation of TSR domain-containing proteins
O-linked glycosylation
Drugs
Diseases
GWAS
Rhegmatogenous retinal detachment (
23585552
)
Protein-Protein Interactions
29 interactors:
ADAMTSL4
AES
BIRC7
CARD9
CCDC85B
EFEMP2
GOLGA2
KCTD6
KCTD9
KIAA1958
KRT19
KRT31
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP5-9
LZTS2
MDFI
MKRN3
NOTCH2NL
RBPMS
RINT1
SSX2IP
TCF4
TRIM37
TRIM54
TRIP6
USHBP1
106 interactors:
ADAMTSL5
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
C19orf66
C6orf165
CATSPER1
CCDC26
CHCHD2
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
DGCR6
DIP2A
DLK2
DNPEP
DSCR8
EIF4E2
FAH
FAM124B
FARS2
FBLN1
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GMCL1P1
GNE
GNMT
GOLGA8EP
HGF
HOXA1
KIF1A
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2D
LCE3C
LCE3E
LCE4A
LGALS14
LINC00671
LMO1
LMO2
LONRF1
LRRC29
MAPKBP1
MID2
MORN3
MVP
NATD1
NMUR2
NTF4
NTN4
OLFM3
PID1
PIN1
PLSCR1
PRKAB2
PTGER3
RAB2B
RCHY1
RHOJ
SALL2
SLC23A1
SLC6A20
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIP6
TSSK3
TUBGCP4
ZNF417
ZNF587
Entrez ID
79843
54507
HPRD ID
08663
18237
Ensembl ID
ENSG00000124019
ENSG00000143382
Uniprot IDs
Q9H5Z6
F8WAD0
Q6UY14
Q9UFG7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Protein Localization To Nucleus
Regulation Of Nucleocytoplasmic Transport
Regulation Of Intracellular Transport
Regulation Of Binding
Regulation Of Intracellular Protein Transport
Negative Regulation Of Binding
Regulation Of Signal Transduction
Positive Regulation Of Nucleocytoplasmic Transport
Regulation Of Wnt Signaling Pathway
Positive Regulation Of JNK Cascade
Cellular Component Assembly
Regulation Of Signaling
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Cellular Localization
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Binding
Cell Differentiation Involved In Embryonic Placenta Development
Positive Regulation Of Intracellular Protein Transport
Regulation Of JNK Cascade
Activation Of JUN Kinase Activity
Regulation Of Protein Import Into Nucleus
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Localization
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Natural Killer Cell Apoptotic Process
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Binding
Positive Regulation Of Intracellular Transport
Negative Regulation Of Fat Cell Differentiation
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of JUN Kinase Activity
Wnt Signaling Pathway
Regulation Of Protein Transport
Negative Regulation Of Protein Localization To Nucleus
Regulation Of JUN Kinase Activity
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Histone H2A-K119 Monoubiquitination
JNK Cascade
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Establishment Of Protein Localization
Negative Regulation Of RNA Biosynthetic Process
Maintenance Of DNA Repeat Elements
Multicellular Organismal Development
Keratinization
Organ Development
Developmental Process
Keratinocyte Differentiation
System Development
Anatomical Structure Development
Epidermis Development
Tissue Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Epidermal Cell Differentiation
Sensory Organ Development
Response To Organic Substance
Organic Anion Transport
Positive Regulation Of Neuron Projection Regeneration
Regulation Of Transcription From RNA Polymerase II Promoter
Epithelium Development
Cellular Response To Thyroid Hormone Stimulus
MRNA Transcription From RNA Polymerase II Promoter
Skin Development
Positive Regulation Of Transcription, DNA-templated
Transepithelial Transport
Semicircular Canal Development
Positive Regulation Of Gene Expression
Regulation Of Branching Involved In Salivary Gland Morphogenesis
MRNA Transcription
Response To Thyroid Hormone
Negative Regulation Of Hydrolase Activity
Cell Differentiation
Negative Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud
?
abl
baalc
bcr
cd83
ciita
council
ctnnd1
e2993
gab1
gli1
hubs
il15
irs1
p185bcr
p210bcr
pilrb
ptp4a3
rab21
serpinb9
spp1
spry1
supervised
transcriptomic
tspan16
ukall
underexpressed
unsupervised
xbp1
xii
Tagcloud (Difference)
?
abl
baalc
bcr
cd83
ciita
council
ctnnd1
e2993
gab1
gli1
hubs
il15
irs1
p185bcr
p210bcr
pilrb
ptp4a3
rab21
serpinb9
spp1
spry1
supervised
transcriptomic
tspan16
ukall
underexpressed
unsupervised
xbp1
xii
Tagcloud (Intersection)
?