FAM124B and NADK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM124B	NADK
Description		family with sequence similarity 124 member B	NAD kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Cytosol
	Molecular Function	Protein Binding	Nucleotide Binding NAD+ Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding
	Biological Process		NADP+ Biosynthetic Process Phosphorylation NAD+ Metabolic Process Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus ATP Metabolic Process
Pathways			Nicotinate metabolism
Drugs
Diseases
GWAS		Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Familial squamous cell lung carcinoma ( 29924316)	Blood protein levels ( 30072576) Body mass index ( 26426971 28892062) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Multiple sclerosis ( 31604244) Pulse pressure ( 28135244) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 28135244 30578418)
Interacting Genes		67 interacting genes: ABI1 ABI3 ADAMTSL4 BIRC7 BLZF1 CARD9 CCDC85B CYSRT1 DRC12 EFEMP2 EFHC2 ESM1 GIGYF1 GKAP1 GOLGA2 GPRASP2 GPRASP3 GRB7 HSF2BP IHO1 IKZF3 ISCA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP9-3 LHX3 LZTS2 MBD3L1 MDFI MIPOL1 MKRN3 MTUS2 MYF5 NADK NOTCH2NLA RBPMS RINT1 RSPH3 SEPTIN14 SH2B2 SP7 SSX2IP TCF4 TLE5 TRAF2 TRIM37 TRIM42 TRIM54 TRIM8 TRIM9 TRIP6 USHBP1 USP54 WDR83 ZBED1 ZNF69 ZNF774 ZRANB1	10 interacting genes: CRY2 EEF1G FAM124B GLRX3 GRB2 LNX1 NUDT18 SDCBP SRPK2 YWHAQ
Entrez ID		79843	65220
HPRD ID		08663	16907
Ensembl ID		ENSG00000124019	ENSG00000008130
Uniprot IDs		Q9H5Z6	A0A0A0MR98 O95544
PDB IDs			3PFN 8KGC 9CR3 9CR4 9CRA
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Keratin Filament Intermediate Filament Protein Binding Ubiquitin Protein Ligase Activity Signaling Adaptor Activity Post-translational Protein Modification Cytoskeleton Protein Modification By Small Protein Conjugation Protein Ubiquitination	Photoreactive Repair Blue Light Signaling Pathway DNA (6-4) Photolyase Activity Deoxyribodipyrimidine Photo-lyase Activity Blue Light Photoreceptor Activity Guanyl-nucleotide Exchange Factor Adaptor Activity Intracellular Signaling Cassette Small GTPase-mediated Signal Transduction Grb2-EGFR Complex Ras Protein Signal Transduction Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex 14-3-3 Protein Binding 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Negative Regulation Of Transport Cry-Per Complex 8-oxo-dGDP Phosphatase Activity Identical Protein Binding Intracellular Signal Transduction Negative Regulation Of Glucocorticoid Secretion Cytosol Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Nuclear Speck Organization Regulation Of Sodium-dependent Phosphate Transport
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