FAM124B and RSPH3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM124B	RSPH3
Description		family with sequence similarity 124 member B	radial spoke head 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Radial Spoke Head Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Bitter beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Familial squamous cell lung carcinoma ( 29924316)	Attention deficit hyperactivity disorder ( 32279069) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 25920553) Lipoprotein (a) levels ( 26377243) Prepulse inhibition of the startle response ( 31596458) Systemic lupus erythematosus ( 28714469)
Interacting Genes		67 interacting genes: ABI1 ABI3 ADAMTSL4 BIRC7 BLZF1 CARD9 CCDC85B CYSRT1 DRC12 EFEMP2 EFHC2 ESM1 GIGYF1 GKAP1 GOLGA2 GPRASP2 GPRASP3 GRB7 HSF2BP IHO1 IKZF3 ISCA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP9-3 LHX3 LZTS2 MBD3L1 MDFI MIPOL1 MKRN3 MTUS2 MYF5 NADK NOTCH2NLA RBPMS RINT1 RSPH3 SEPTIN14 SH2B2 SP7 SSX2IP TCF4 TLE5 TRAF2 TRIM37 TRIM42 TRIM54 TRIM8 TRIM9 TRIP6 USHBP1 USP54 WDR83 ZBED1 ZNF69 ZNF774 ZRANB1	8 interacting genes: APP DPY30 FAM124B HSPB1 MLH1 PRKAR1A ROPN1L RSPH14
Entrez ID		79843	83861
HPRD ID		08663	15279
Ensembl ID		ENSG00000124019	ENSG00000130363
Uniprot IDs		Q9H5Z6	Q86UC2
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Keratin Filament Intermediate Filament Protein Binding Ubiquitin Protein Ligase Activity Signaling Adaptor Activity Post-translational Protein Modification Cytoskeleton Protein Modification By Small Protein Conjugation Protein Ubiquitination	Radial Spoke Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Microtubule-based Transport Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Positive Regulation Of Interleukin-1 Beta Production Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Microtubule-based Movement Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Male Meiosis Chromosome Segregation MutLalpha Complex Chiasma Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Gene Expression Positive Regulation Of Chemotaxis Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response
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