FAM124B and CARD9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM124B	CARD9
Gene Name		family with sequence similarity 124B	caspase recruitment domain family, member 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm
	Molecular Function	Protein Binding	Protein Homodimerization Activity CARD Domain Binding
	Biological Process		Response To Fungus Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Drug Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of JNK Cascade Defense Response To Gram-positive Bacterium Defense Response To Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways			Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Innate Immune System
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 21743469) Crohn's disease ( 22936669 21102463) Inflammatory bowel disease ( 23128233) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		29 interactors: ADAMTSL4 AES BIRC7 CARD9 CCDC85B EFEMP2 GOLGA2 KCTD6 KCTD9 KIAA1958 KRT19 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MDFI MKRN3 NOTCH2NL RBPMS RINT1 SSX2IP TCF4 TRIM37 TRIM54 TRIP6 USHBP1	65 interactors: ABLIM1 AES ALS2CR11 AMOTL2 BCL10 BLZF1 C1orf94 CCDC36 CCDC85B CCHCR1 CDCA7L CEP57L1 CEP70 CSNK2A1 CWF19L2 DAXX DUSP13 EIF4E2 FAM124B FAM161A FAM208B FAM50B HMBOX1 IQCE KCTD9 KIAA0408 KIF9 KRT19 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 LENG1 LMO1 LZTS2 MEOX2 MFAP1 NECAB2 PAK7 PBX2 PHC2 PNMA5 PPP1R18 RTP5 SSX2IP STX11 SUMO1 TCEANC TCL1A TFIP11 TNFAIP1 TRIM23 TRIM29 TRIM42 TRIM54 TSNAX USP15 VPS28 ZCCHC7 ZNF250 ZNF417 ZNF572 ZNF587 ZNF655
Entrez ID		79843	64170
HPRD ID		08663	06236
Ensembl ID		ENSG00000124019	ENSG00000187796
Uniprot IDs		Q9H5Z6	Q9H257
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Transport Regulation Of Binding Regulation Of Intracellular Protein Transport Negative Regulation Of Binding Regulation Of Signal Transduction Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Wnt Signaling Pathway Positive Regulation Of JNK Cascade Cellular Component Assembly Regulation Of Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Cellular Localization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Intracellular Protein Transport Regulation Of JNK Cascade Activation Of JUN Kinase Activity Regulation Of Protein Import Into Nucleus Regulation Of Stress-activated MAPK Cascade Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Natural Killer Cell Apoptotic Process Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Positive Regulation Of Intracellular Transport Negative Regulation Of Fat Cell Differentiation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of JUN Kinase Activity Wnt Signaling Pathway Regulation Of Protein Transport Negative Regulation Of Protein Localization To Nucleus Regulation Of JUN Kinase Activity Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Histone H2A-K119 Monoubiquitination JNK Cascade Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription Factor Import Into Nucleus Regulation Of Establishment Of Protein Localization Negative Regulation Of RNA Biosynthetic Process Maintenance Of DNA Repeat Elements	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Organelle Organization Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Wnt Signaling Pathway Spliceosomal Complex Disassembly Organelle Assembly Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Mast Cell Cytokine Production Histone H2B Conserved C-terminal Lysine Deubiquitination Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?			adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Difference) ?			adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Intersection) ?