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ZNF408 and TOP3B
Number of citations of the paper that reports this interaction (PMID
15231747
)
44
Data Source:
HPRD
(two hybrid)
ZNF408
TOP3B
Gene Name
zinc finger protein 408
topoisomerase (DNA) III beta
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Condensed Chromosome
Nucleus
Nucleoplasm
Molecular Function
DNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
DNA Binding
DNA Topoisomerase Activity
DNA Topoisomerase Type I Activity
Poly(A) RNA Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
DNA Topological Change
Chromosome Segregation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
ATRN
CALCOCO2
CCDC136
CEP70
CHAF1A
CRELD1
DDX56
DVL3
EXOSC2
FBLN2
FHL2
GIPC1
GPATCH2L
HOXA5
HOXB9
ID3
KHDRBS3
KRTAP4-12
LDOC1
LSM2
MDFI
MIF
PDE4DIP
PDLIM4
PRAME
PRNP
RALYL
SAP30BP
THAP1
TOP3B
UPF2
ZBTB8A
ZBTB9
ZNF212
ZNF330
ZNF331
ZNF792
18 interactors:
ADAMTSL4
C1QBP
CENPF
CHD8
CHIC2
FBLN5
GRN
KRTAP4-12
MID2
PNMA2
RECQL5
SNRPB
SPRED2
SSX2IP
TRIM41
UPF2
ZFPM1
ZNF408
Entrez ID
79797
8940
HPRD ID
18338
04662
Ensembl ID
ENSG00000175213
ENSG00000100038
Uniprot IDs
B4DXY4
Q9H9D4
A8K4N2
O95985
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Heterocycle Metabolic Process
Regulation Of Transcription, DNA-templated
Cellular Aromatic Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Biosynthetic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Regulation Of Metabolic Process
Cardiac Chamber Development
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
Embryonic Skeletal System Development
Positive Regulation Of Prostaglandin Secretion Involved In Immune Response
RNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Mesenchyme Development
Positive Regulation Of MAP Kinase Activity
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Preantral Ovarian Follicle Growth
Polyadenylation-dependent SnoRNA 3'-end Processing
Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription
U4 SnRNA 3'-end Processing
Regulation Of Cell Death
Embryonic Organ Development
Organ Development
Positive Regulation Of JUN Kinase Activity
Atrial Cardiac Muscle Cell Development
Cell-cell Signaling Involved In Mammary Gland Development
TRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
Heart Development
Regulation Of JUN Kinase Activity
Cardiac Septum Development
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Bronchiole Development
Lung Goblet Cell Differentiation
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Interleukin-4 Biosynthetic Process
Negative Regulation Of Mast Cell Differentiation
Negative Regulation Of Nucleic Acid-templated Transcription
DNA Duplex Unwinding
DNA Geometric Change
Positive Regulation Of Trophoblast Cell Migration
Negative Regulation Of MDA-5 Signaling Pathway
Mitral Valve Formation
Cellular Macromolecule Biosynthetic Process
Regulation Of Interferon-gamma Production
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Transcriptional Activation By Promoter-enhancer Looping
Tricuspid Valve Formation
Tricuspid Valve Morphogenesis
Primitive Erythrocyte Differentiation
Tricuspid Valve Development
Blood Coagulation
Hemostasis
Regulation Of Definitive Erythrocyte Differentiation
Regulation Of Mast Cell Differentiation
Intraciliary Transport Involved In Cilium Morphogenesis
Positive Regulation Of Mitochondrial Translation
Mitral Valve Morphogenesis
Definitive Erythrocyte Differentiation
Organelle Assembly
Cellular Localization
Negative Regulation Of Interleukin-4 Production
Positive Regulation Of Dendritic Cell Chemotaxis
Mitral Valve Development
Elastic Fiber Assembly
Chromosome Organization
Protein Localization To Microtubule
Tagcloud
?
accelerate
advancing
aging
bubr1
claimed
ebp
ghr
ghrhr
gompertz
insr
instance
interpreted
klotho
lmna
longevity
msra
pit1
polga
prdx1
prop1
prove
retard
shc1
span
straightforward
tables
terc
trx
wrn
Tagcloud (Difference)
?
accelerate
advancing
aging
bubr1
claimed
ebp
ghr
ghrhr
gompertz
insr
instance
interpreted
klotho
lmna
longevity
msra
pit1
polga
prdx1
prop1
prove
retard
shc1
span
straightforward
tables
terc
trx
wrn
Tagcloud (Intersection)
?