ZNF408 and RBMY1J

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF408	RBMY1J
Description		zinc finger protein 408	RNA binding motif protein Y-linked family 1 member J
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)
Interacting Genes		83 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1	28 interacting genes: APOBEC3C CBX2 CNNM3 EPM2AIP1 HHEX HNRNPK LNX1 NPDC1 PCDHB14 PPP1R37 PRPF31 PRR3 RASD1 RBM3 RBMX RBMY1A1 RBMY1E RBMY1F RNPS1 SNRPA SPATC1L TRA2B U2AF2 YTHDC1 ZNF317 ZNF408 ZNF792 ZNF837
Entrez ID		79797	378951
HPRD ID		18338	15233
Ensembl ID		ENSG00000175213	ENSG00000226941
Uniprot IDs		B4DXY4 Q9H9D4	Q15415
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Nucleus Protein Binding Zinc Ion Binding Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex MRNA Processing Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process RNA Processing Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Muramyl Dipeptide	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Spliceosomal Complex Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing MRNA Processing Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nucleic Acid Binding RNA Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleus Regulation Of Gene Expression MRNA Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Ribonucleoprotein Complex Localization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cytoplasmic Translational Initiation Ribonucleoprotein Complex Poly-pyrimidine Tract Binding U4atac SnRNP
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