ZNF408 and PDLIM4

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		ZNF408	PDLIM4
Gene Name		zinc finger protein 408	PDZ and LIM domain 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Zinc Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 22412388) Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		37 interactors: ATRN CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 GIPC1 GPATCH2L HOXA5 HOXB9 ID3 KHDRBS3 KRTAP4-12 LDOC1 LSM2 MDFI MIF PDE4DIP PDLIM4 PRAME PRNP RALYL SAP30BP THAP1 TOP3B UPF2 ZBTB8A ZBTB9 ZNF212 ZNF330 ZNF331 ZNF792	5 interactors: ABCA1 PTPN13 RBPMS TRIP6 ZNF408
Entrez ID		79797	8572
HPRD ID		18338	04571
Ensembl ID		ENSG00000175213	ENSG00000131435
Uniprot IDs		B4DXY4 Q9H9D4	P50479
PDB IDs			2EEG 2V1W
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Metabolic Process Cardiac Chamber Development Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Embryonic Skeletal System Development Positive Regulation Of Prostaglandin Secretion Involved In Immune Response RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Mesenchyme Development Positive Regulation Of MAP Kinase Activity Nuclear Polyadenylation-dependent TRNA Catabolic Process Preantral Ovarian Follicle Growth Polyadenylation-dependent SnoRNA 3'-end Processing Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription U4 SnRNA 3'-end Processing Regulation Of Cell Death Embryonic Organ Development Organ Development Positive Regulation Of JUN Kinase Activity Atrial Cardiac Muscle Cell Development Cell-cell Signaling Involved In Mammary Gland Development TRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' Heart Development Regulation Of JUN Kinase Activity Cardiac Septum Development Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Bronchiole Development Lung Goblet Cell Differentiation	Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Transport Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Interleukin-1 Beta Secretion Regulation Of Signal Transduction Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of Intracellular Transport Apolipoprotein A-I-mediated Signaling Pathway Interleukin-1 Secretion Regulation Of Intracellular Protein Transport Regulation Of Signaling Negative Regulation Of Cholesterol Storage High-density Lipoprotein Particle Assembly Intracellular Cholesterol Transport Intracellular Sterol Transport Phospholipid Homeostasis Positive Regulation Of Protein Transport Platelet Dense Granule Organization Cellular Macromolecule Biosynthetic Process Phospholipid Efflux Phagocytosis, Engulfment Macromolecule Biosynthetic Process Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Intracellular Transport Negative Regulation Of Macrophage Derived Foam Cell Differentiation Cellular Response To Cholesterol Response To Laminar Fluid Shear Stress Regulation Of SMAD Protein Import Into Nucleus Membrane Invagination Reverse Cholesterol Transport Regulation Of Intracellular Signal Transduction Protein-lipid Complex Assembly Response To Lipoprotein Particle Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux Negative Regulation Of Lipid Storage Positive Regulation Of Cholesterol Transport Positive Regulation Of NF-kappaB Import Into Nucleus Regulation Of Cholesterol Efflux Response To Cholesterol Cholesterol Efflux Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Transport
Tagcloud ?			adjacent benign c21orf63 distinguish done fabp5 flj14084 gstp1 hypermethylation implicating kiaa1210 methylation microarrays mlp panel prima1 profiling prostate ptgs2 quantitative sensitivities sorbs1 sox4 specificities svil taqman tissues tu3a u133
Tagcloud (Difference) ?			adjacent benign c21orf63 distinguish done fabp5 flj14084 gstp1 hypermethylation implicating kiaa1210 methylation microarrays mlp panel prima1 profiling prostate ptgs2 quantitative sensitivities sorbs1 sox4 specificities svil taqman tissues tu3a u133
Tagcloud (Intersection) ?