ZNF408 and ZBTB48

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF408	ZBTB48
Description		zinc finger protein 408	zinc finger and BTB domain containing 48
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Telomeric Region Nucleus Chromosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)	Body size at age 10 ( 32376654)
Interacting Genes		83 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1	35 interacting genes: C11orf58 CDK2AP2 CDKN1A CEP70 DVL2 DVL3 EP300 GPATCH2L ILK KRTAP1-1 KRTAP10-5 KRTAP10-7 L3MBTL2 LLCFC1 MAP1LC3A MCC NME7 PNRC2 RGS2 RNF10 SPANXN2 THAP1 TNFRSF14 TRIM41 TSPYL2 UPF2 WDR5 ZBTB26 ZBTB6 ZBTB7A ZBTB8A ZBTB9 ZNF317 ZNF408 ZNF837
Entrez ID		79797	3104
HPRD ID		18338	01316
Ensembl ID		ENSG00000175213	ENSG00000204859
Uniprot IDs		B4DXY4 Q9H9D4	A8K291 B2R702 P10074
PDB IDs			3B84 5YJ3
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Nucleus Protein Binding Zinc Ion Binding Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex MRNA Processing Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process RNA Processing Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Muramyl Dipeptide	Zinc Ion Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Positive Regulation Of Neuron Projection Arborization Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Neuron Projection Arborization
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