ZNF408 and LSM2

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		ZNF408	LSM2
Gene Name		zinc finger protein 408	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytosol Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding U6 SnRNA Binding Ral GTPase Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: ATRN CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 GIPC1 GPATCH2L HOXA5 HOXB9 ID3 KHDRBS3 KRTAP4-12 LDOC1 LSM2 MDFI MIF PDE4DIP PDLIM4 PRAME PRNP RALYL SAP30BP THAP1 TOP3B UPF2 ZBTB8A ZBTB9 ZNF212 ZNF330 ZNF331 ZNF792	31 interactors: AES BANP C14orf1 CLNS1A CRMP1 DDX20 DNAJA1 EXOSC10 GBP2 KRT13 LNX1 LSM1 LSM3 LSM5 LSM6 LSM7 LSM8 MAGEA6 MEOX2 PRCC RALA REL RSRC1 SF3B2 SMN1 SNRPB SNRPD2 SNRPE TRIM54 ZBTB16 ZNF408
Entrez ID		79797	57819
HPRD ID		18338	06282
Ensembl ID		ENSG00000175213	ENSG00000204392
Uniprot IDs		B4DXY4 Q9H9D4	Q9Y333
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Metabolic Process Cardiac Chamber Development Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Embryonic Skeletal System Development Positive Regulation Of Prostaglandin Secretion Involved In Immune Response RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Mesenchyme Development Positive Regulation Of MAP Kinase Activity Nuclear Polyadenylation-dependent TRNA Catabolic Process Preantral Ovarian Follicle Growth Polyadenylation-dependent SnoRNA 3'-end Processing Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription U4 SnRNA 3'-end Processing Regulation Of Cell Death Embryonic Organ Development Organ Development Positive Regulation Of JUN Kinase Activity Atrial Cardiac Muscle Cell Development Cell-cell Signaling Involved In Mammary Gland Development TRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' Heart Development Regulation Of JUN Kinase Activity Cardiac Septum Development Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Bronchiole Development Lung Goblet Cell Differentiation	RNA Splicing MRNA Metabolic Process MRNA Processing RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Splicing, Via Spliceosome RNA Metabolic Process Spliceosomal SnRNP Assembly Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Ribonucleoprotein Complex Assembly RNA Catabolic Process NcRNA Metabolic Process Aromatic Compound Catabolic Process Histone MRNA Catabolic Process Spliceosomal Complex Assembly Cellular Metabolic Process Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly Metabolic Process Termination Of RNA Polymerase II Transcription Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Catabolic Process DNA-templated Transcription, Termination Transcription From RNA Polymerase II Promoter MRNA 3'-end Processing Membrane Raft Localization Positive Regulation Of Anoikis Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Embryonic Pattern Specification Cellular Process Positive Regulation Of Apoptotic Process Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Programmed Cell Death Transcription, DNA-templated Positive Regulation Of Cell Death Male Germ-line Stem Cell Asymmetric Division Somite Specification
Tagcloud ?			angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm23 lsm5 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Difference) ?			angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm23 lsm5 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Intersection) ?