ZNF408 and DDX56

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
HPRD (two hybrid)

		ZNF408	DDX56
Description		zinc finger protein 408	DEAD-box helicase 56
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleolus Cytosol Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity RNA Stem-loop Binding Protein Sequestering Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Cytoplasmic Pattern Recognition Receptor Signaling Pathway RRNA Processing Protein Import Into Nucleus Positive Regulation Of Neuron Projection Development Negative Regulation Of Type I Interferon Production Ribosome Biogenesis Host-mediated Perturbation Of Viral RNA Genome Replication Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)	LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		83 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1	6 interacting genes: EHD2 EIF4A3 OGT SOX30 USP33 ZNF408
Entrez ID		79797	54606
HPRD ID		18338	12154
Ensembl ID		ENSG00000175213	ENSG00000136271
Uniprot IDs		B4DXY4 Q9H9D4	Q9NY93
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Nucleus Protein Binding Zinc Ion Binding Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex MRNA Processing Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process RNA Processing Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Muramyl Dipeptide	Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Negative Regulation Of Translation Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Translation Protein O-acetylglucosaminyltransferase Activity Selenocysteine Insertion Sequence Binding Negative Regulation Of Translational Elongation Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Translation At Postsynapse Proacrosomal Vesicle Fusion VCB Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?