TOP3B and SNRPB

Number of citations of the paper that reports this interaction (PMID 11549288)
1

Data Source:
HPRD (two hybrid)

		TOP3B	SNRPB
Gene Name		topoisomerase (DNA) III beta	small nuclear ribonucleoprotein polypeptides B and B1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	DNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I Activity Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding Histone Pre-mRNA DCP Binding
	Biological Process	DNA Topological Change Chromosome Segregation	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ADAMTSL4 C1QBP CENPF CHD8 CHIC2 FBLN5 GRN KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF408	48 interactors: ASCC2 BANP C14orf1 CALCOCO2 CD2BP2 CDKN2A CEP55 CLNS1A COIL CTDP1 DAB1 DDX20 DHX9 FNBP4 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GIGYF2 GOLGA2 IL7R KRT40 L3MBTL3 LSM11 LSM2 LSM8 PNMA1 PRMT5 PRMT7 PSMA3 RBPMS RFX6 SKIV2L SMN1 SMN2 SMNDC1 SNRPD1 SNRPD3 SNUPN SS18L1 STRAP STXBP2 STXBP3 TFIP11 TOP3B TRIM23 WBP4 WDR77
Entrez ID		8940	6628
HPRD ID		04662	01655
Ensembl ID		ENSG00000100038	ENSG00000125835
Uniprot IDs		A8K4N2 O95985	P14678 Q66K91
PDB IDs			1D3B 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Interleukin-4 Biosynthetic Process Negative Regulation Of Mast Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription DNA Duplex Unwinding DNA Geometric Change Positive Regulation Of Trophoblast Cell Migration Negative Regulation Of MDA-5 Signaling Pathway Mitral Valve Formation Cellular Macromolecule Biosynthetic Process Regulation Of Interferon-gamma Production Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Transcriptional Activation By Promoter-enhancer Looping Tricuspid Valve Formation Tricuspid Valve Morphogenesis Primitive Erythrocyte Differentiation Tricuspid Valve Development Blood Coagulation Hemostasis Regulation Of Definitive Erythrocyte Differentiation Regulation Of Mast Cell Differentiation Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Mitochondrial Translation Mitral Valve Morphogenesis Definitive Erythrocyte Differentiation Organelle Assembly Cellular Localization Negative Regulation Of Interleukin-4 Production Positive Regulation Of Dendritic Cell Chemotaxis Mitral Valve Development Elastic Fiber Assembly Chromosome Organization Protein Localization To Microtubule	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing RNA Processing MRNA Metabolic Process Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Gene Expression RNA Metabolic Process Cellular Macromolecular Complex Assembly Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process NcRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Cellular Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Neutrophil Degranulation Chromosome Organization Histone H4-R3 Methylation Neutrophil Activation Involved In Immune Response Peptidyl-arginine N-methylation Chromatin Organization Spliceosomal Tri-snRNP Complex Assembly Metabolic Process Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Mitotic Cell Cycle Phase Transition Transcription, DNA-templated Neutrophil Mediated Immunity Histone MRNA Metabolic Process Chromatin Modification Neutrophil Activation Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Cellular Process RNA Biosynthetic Process Regulation Of T Cell Differentiation In Thymus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Process Pancreatic Epsilon Cell Differentiation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration SnRNA Import Into Nucleus Spliceosomal Complex Disassembly
Tagcloud ?		accelerate advancing aging bubr1 claimed ebp ghr ghrhr gompertz insr instance interpreted klotho lmna longevity msra pit1 polga prdx1 prop1 prove retard shc1 span straightforward tables terc trx wrn
Tagcloud (Difference) ?		accelerate advancing aging bubr1 claimed ebp ghr ghrhr gompertz insr instance interpreted klotho lmna longevity msra pit1 polga prdx1 prop1 prove retard shc1 span straightforward tables terc trx wrn
Tagcloud (Intersection) ?