TOP3B

Name	DNA topoisomerase III beta
Structure
Interactors	25 interactors: ADAMTSL4 AXIN2 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GPRASP3 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TDRD3 TRIM41 UPF2 ZFPM1 ZNF250 ZNF408
GO Annotations	Cellular Component	Condensed Chromosome Nucleus DNA Topoisomerase III-beta-TDRD3 Complex
	Molecular Function	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding Isomerase Activity RNA Topoisomerase Activity
	Biological Process	DNA Topological Change DNA Repair DNA Recombination Chromosome Segregation
GWAS	Attention function in attention deficit hyperactive disorder ( 26174813 ) Bipolar disorder ( 31043756 ) Diastolic blood pressure ( 29208002 ) Response to selective serotonin reuptake inhibitors in depression ( 27622933 )
Entrez ID	8940
HPRD ID	04662
Ensembl ID	ENSG00000100038
Uniprot IDs	A8K4N2 O95985
PDB IDs	5GVC 5GVE 9C9W 9C9Y 9CA0 9CA1 9CA4 9CAG 9CAH 9CAJ 9CAK 9CAL