TOP3B and FBLN5

Number of citations of the paper that reports this interaction (PMID 11549288)
1

Data Source:
HPRD (two hybrid)

		TOP3B	FBLN5
Gene Name		topoisomerase (DNA) III beta	fibulin 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Elastic Fiber
	Molecular Function	DNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I Activity Poly(A) RNA Binding	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity
	Biological Process	DNA Topological Change Chromosome Segregation	Regulation Of Cell Growth Cell-matrix Adhesion Extracellular Matrix Organization Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals
Pathways			Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		18 interactors: ADAMTSL4 C1QBP CENPF CHD8 CHIC2 FBLN5 GRN KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF408	7 interactors: ATN1 GFI1B LOXL1 LPA PAXIP1 SOD3 TOP3B
Entrez ID		8940	10516
HPRD ID		04662	05204
Ensembl ID		ENSG00000100038	ENSG00000140092
Uniprot IDs		A8K4N2 O95985	Q9UBX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Interleukin-4 Biosynthetic Process Negative Regulation Of Mast Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription DNA Duplex Unwinding DNA Geometric Change Positive Regulation Of Trophoblast Cell Migration Negative Regulation Of MDA-5 Signaling Pathway Mitral Valve Formation Cellular Macromolecule Biosynthetic Process Regulation Of Interferon-gamma Production Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Transcriptional Activation By Promoter-enhancer Looping Tricuspid Valve Formation Tricuspid Valve Morphogenesis Primitive Erythrocyte Differentiation Tricuspid Valve Development Blood Coagulation Hemostasis Regulation Of Definitive Erythrocyte Differentiation Regulation Of Mast Cell Differentiation Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Mitochondrial Translation Mitral Valve Morphogenesis Definitive Erythrocyte Differentiation Organelle Assembly Cellular Localization Negative Regulation Of Interleukin-4 Production Positive Regulation Of Dendritic Cell Chemotaxis Mitral Valve Development Elastic Fiber Assembly Chromosome Organization Protein Localization To Microtubule	Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Positive Regulation Of Histone H3-K36 Methylation Protein Deamination Regulation Of Histone Modification Regulation Of Chromosome Organization
Tagcloud ?		accelerate advancing aging bubr1 claimed ebp ghr ghrhr gompertz insr instance interpreted klotho lmna longevity msra pit1 polga prdx1 prop1 prove retard shc1 span straightforward tables terc trx wrn	5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation
Tagcloud (Difference) ?		accelerate advancing aging bubr1 claimed ebp ghr ghrhr gompertz insr instance interpreted klotho lmna longevity msra pit1 polga prdx1 prop1 prove retard shc1 span straightforward tables terc trx wrn	5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation
Tagcloud (Intersection) ?