ZNF408 and PRAME

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		ZNF408	PRAME
Gene Name		zinc finger protein 408	preferentially expressed antigen in melanoma
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Plasma Membrane
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Retinoic Acid Receptor Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Apoptotic Process Positive Regulation Of Cell Proliferation Cell Differentiation Regulation Of Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: ATRN CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 GIPC1 GPATCH2L HOXA5 HOXB9 ID3 KHDRBS3 KRTAP4-12 LDOC1 LSM2 MDFI MIF PDE4DIP PDLIM4 PRAME PRNP RALYL SAP30BP THAP1 TOP3B UPF2 ZBTB8A ZBTB9 ZNF212 ZNF330 ZNF331 ZNF792	9 interactors: CUL2 RARA RBX1 STK19 TCEB1 TCEB2 UBC XRN2 ZNF408
Entrez ID		79797	23532
HPRD ID		18338	05820
Ensembl ID		ENSG00000175213	ENSG00000185686
Uniprot IDs		B4DXY4 Q9H9D4	F5H4B1 P78395
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Metabolic Process Cardiac Chamber Development Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Embryonic Skeletal System Development Positive Regulation Of Prostaglandin Secretion Involved In Immune Response RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Mesenchyme Development Positive Regulation Of MAP Kinase Activity Nuclear Polyadenylation-dependent TRNA Catabolic Process Preantral Ovarian Follicle Growth Polyadenylation-dependent SnoRNA 3'-end Processing Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription U4 SnRNA 3'-end Processing Regulation Of Cell Death Embryonic Organ Development Organ Development Positive Regulation Of JUN Kinase Activity Atrial Cardiac Muscle Cell Development Cell-cell Signaling Involved In Mammary Gland Development TRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' Heart Development Regulation Of JUN Kinase Activity Cardiac Septum Development Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Bronchiole Development Lung Goblet Cell Differentiation	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Response To Hypoxia Viral Process Cellular Macromolecule Catabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Abiotic Stimulus Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Stress Positive Regulation Of Viral Transcription Cellular Protein Metabolic Process Transcription From RNA Polymerase II Promoter Catabolic Process Transcription Elongation From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Viral Transcription Positive Regulation Of Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Cellular Protein Modification Process Sertoli Cell Fate Commitment DNA-templated Transcription, Elongation Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Protein Metabolic Process Notch Signaling Pathway
Tagcloud ?			aberrantly acetylglucosaminyltransferase antigens bage ctl ecto fig fm3 fm57 gage gp100 immunogenic immunogenicity in4 maa mage mart melan melanocyte melanomas p15 pbl permitted pointing ref tab trp tyrosinase uncloned
Tagcloud (Difference) ?			aberrantly acetylglucosaminyltransferase antigens bage ctl ecto fig fm3 fm57 gage gp100 immunogenic immunogenicity in4 maa mage mart melan melanocyte melanomas p15 pbl permitted pointing ref tab trp tyrosinase uncloned
Tagcloud (Intersection) ?