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UCP2 and YWHAQ
Number of citations of the paper that reports this interaction (PubMedID
10785390
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(in vitro)
UCP2
YWHAQ
Description
uncoupling protein 2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Membrane
Mitochondrial Membrane
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Molecular Function
Protein Binding
Secondary Active Sulfate Transmembrane Transporter Activity
Proton Transmembrane Transporter Activity
Chloride Transmembrane Transporter Activity
Oxaloacetate Transmembrane Transporter Activity
Malate Transmembrane Transporter Activity
L-aspartate Transmembrane Transporter Activity
Antiporter Activity
Oxidative Phosphorylation Uncoupler Activity
GDP Binding
Protein Homodimerization Activity
Phosphate Ion Uniporter Activity
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Biological Process
Mitochondrial Fission
Response To Superoxide
Response To Hypoxia
Glycolytic Process
Glutamine Metabolic Process
Mitochondrial Transport
Response To Cold
Response To Glucose
Inorganic Anion Transport
C4-dicarboxylate Transport
Long-chain Fatty Acid Transport
Macrophage Differentiation
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Cellular Response To Amino Acid Starvation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Mitochondrial Membrane Potential
Transmembrane Transport
Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Response To Fatty Acid
L-aspartate Transmembrane Transport
Cellular Response To Lead Ion
Cellular Response To Glucose Stimulus
Malate Transmembrane Transport
Response To Dexamethasone
Reactive Oxygen Species Metabolic Process
Liver Regeneration
Negative Regulation Of Calcium Import Into The Mitochondrion
Positive Regulation Of Cold-induced Thermogenesis
Oxaloacetate(2-) Transmembrane Transport
Sulfate Transmembrane Transport
Chloride Transmembrane Transport
Proton Transmembrane Transport
Mitochondrial Transmembrane Transport
Adaptive Thermogenesis
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Pathways
The fatty acid cycling model
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Mean platelet volume (
32888494
)
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Interacting Genes
6 interacting genes:
KRTAP10-3
KRTAP10-7
YWHAB
YWHAG
YWHAQ
YWHAZ
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
Entrez ID
7351
10971
HPRD ID
03410
00886
Ensembl ID
ENSG00000175567
ENSG00000134308
Uniprot IDs
P55851
P27348
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
Enriched GO Terms of Interacting Partners
?
Protein Domain Specific Binding
Protein Targeting
Protein Sequestering Activity
Phosphoserine Residue Binding
Identical Protein Binding
Focal Adhesion
Negative Regulation Of Protein Localization To Nucleus
Cellular Response To Glucose Starvation
Negative Regulation Of TORC1 Signaling
TORC1 Signaling
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Melanosome
Regulation Of TORC1 Signaling
Negative Regulation Of TOR Signaling
TOR Signaling
Keratin Filament
Synaptic Target Recognition
Establishment Of Protein Localization
Vascular Endothelial Growth Factor Receptor 1 Binding
Negative Regulation Of Macromolecule Metabolic Process
Protein Kinase C Inhibitor Activity
Transmembrane Transporter Binding
Vascular Endothelial Growth Factor Receptor Binding
Negative Regulation Of Metabolic Process
Regulation Of Protein Localization To Nucleus
Regulation Of TOR Signaling
Intermediate Filament
Golgi Reassembly
Vesicle
Positive Regulation Of Vascular Wound Healing
Positive Regulation Of Mast Cell Chemotaxis
Cellular Response To Starvation
Regulation Of Mast Cell Chemotaxis
Intracellular Protein Localization
Negative Regulation Of Protein Localization
Negative Regulation Of Immune Response
Response To Starvation
Establishment Of Golgi Localization
Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell
Phosphorylation-dependent Protein Binding
Regulation Of Protein Localization
Cellular Response To Nutrient Levels
Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell
Cytosol
Regulation Of ERK1 And ERK2 Cascade
Regulation Of Vascular Wound Healing
Extracellular Exosome
Vacuolar Membrane
Negative Regulation Of Immune Response To Tumor Cell
Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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