TRAF5 and THAP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRAF5	THAP1
Gene Name		TNF receptor-associated factor 5	THAP domain containing, apoptosis associated protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex	Nucleus PML Body
	Molecular Function	Ubiquitin-protein Transferase Activity Signal Transducer Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Apoptotic Process Signal Transduction Positive Regulation Of Cell Proliferation Protein Ubiquitination Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GORASP2 LTBR MAP3K14 MAP3K5 MAVS MDM2 NGFRAP1 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 USP7 ZFAND6	58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		7188	55145
HPRD ID		03834	15496
Ensembl ID		ENSG00000082512	ENSG00000131931
Uniprot IDs		D3DT93 O00463	Q9NVV9
PDB IDs			2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Programmed Cell Death Cell Death Death Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of JNK Cascade Cellular Response To Stimulus Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune System Process Regulation Of Protein Metabolic Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of Signal Transduction Regulation Of JNK Cascade Immune Response Signal Transduction Apoptotic Process Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cellular Protein Metabolic Process Signaling Positive Regulation Of MAPK Cascade Cell Communication Cellular Response To Organic Substance Regulation Of Apoptotic Process Response To Stimulus Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Regulation Of Cytokine Production Response To Cytokine Regulation Of Phosphorylation Regulation Of Cell Death Cellular Response To Cytokine Stimulus Positive Regulation Of MAP Kinase Activity Cytokine-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of MAPK Cascade Response To Organic Substance Regulation Of Immunoglobulin Secretion Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Immune System Process Regulation Of Lymphocyte Activation Defense Response Positive Regulation Of Protein Serine/threonine Kinase Activity	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process
Tagcloud ?		adhesion affinity bind cd40 cd40ct cytoplasmic dispensable dominantly extensive icam ikappabalpha implicated incapable intercellular jak3 kappab mediators molecule much mutants necrosis residues strongly tail traf2 traf3 traf6 transduction	assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Difference) ?		adhesion affinity bind cd40 cd40ct cytoplasmic dispensable dominantly extensive icam ikappabalpha implicated incapable intercellular jak3 kappab mediators molecule much mutants necrosis residues strongly tail traf2 traf3 traf6 transduction	assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Intersection) ?