THAP1 and BAG5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP1	BAG5
Gene Name		THAP domain containing, apoptosis associated protein 1	BCL2-associated athanogene 5
Image
Gene Ontology Annotations	Cellular Component	Nucleus PML Body	Nucleus Mitochondrion Membrane Inclusion Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Protein Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Protein Folding Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408	12 interactors: BANP CCDC155 CIRBP FAM118B HSPA4 LRRK2 MAD1L1 PARK2 SNCA STUB1 THAP1 TRIM27
Entrez ID		55145	9529
HPRD ID		15496	04862
Ensembl ID		ENSG00000131931	ENSG00000166170
Uniprot IDs		Q9NVV9	Q9UL15
PDB IDs		2JTG 2KO0 2L1G	2D9D 3A8Y
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process	Negative Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K63-linked Ubiquitination Regulation Of Protein Catabolic Process Cellular Response To Dopamine Dopamine Uptake Involved In Synaptic Transmission Organelle Organization Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Synaptic Vesicle Transport Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cellular Response To Oxidative Stress Cellular Response To Manganese Ion Regulation Of Neurotransmitter Secretion Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Protein Localization To Mitochondrion Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Negative Regulation Of Protein Phosphorylation Response To Ammonium Ion Dopamine Transport Regulation Of Mitochondrial Fission Neurotransmitter Uptake Synaptic Transmission, Dopaminergic Response To Stress Mitochondrion Organization Negative Regulation Of Transport Negative Regulation Of Phosphorylation Cellular Response To Metal Ion Cellular Localization Response To Unfolded Protein Positive Regulation Of Protein Ubiquitination Regulation Of Organelle Organization Response To Manganese Ion Cellular Response To Inorganic Substance Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Dopamine Secretion Cellular Response To Ammonium Ion Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Secretion By Cell Regulation Of Cellular Localization Protein Polyubiquitination Negative Regulation Of Oxidoreductase Activity Protein Localization To Organelle Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoamine Transport Negative Regulation Of Secretion
Tagcloud ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper	athanogene compacta decreasing familial interacted mitochondria mptp nigra null park6 parkinson parkinsonism pars pink1 predominantly preventing proteasome pten pull rescued rotenone snpc sporadic stabilize stabilized substantia ubiquitination ups
Tagcloud (Difference) ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper	athanogene compacta decreasing familial interacted mitochondria mptp nigra null park6 parkinson parkinsonism pars pink1 predominantly preventing proteasome pten pull rescued rotenone snpc sporadic stabilize stabilized substantia ubiquitination ups
Tagcloud (Intersection) ?