Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TRAF5 and ZFAND6
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
TRAF5
ZFAND6
Gene Name
TNF receptor-associated factor 5
zinc finger, AN1-type domain 6
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Cellular_component
Cytoplasm
Molecular Function
Ubiquitin-protein Transferase Activity
Signal Transducer Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Molecular_function
DNA Binding
Protein Binding
Zinc Ion Binding
Polyubiquitin Binding
Biological Process
Apoptotic Process
Signal Transduction
Positive Regulation Of Cell Proliferation
Protein Ubiquitination
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Targeting To Peroxisome
Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Response To Tumor Necrosis Factor
Pathways
Drugs
Diseases
GWAS
Type 2 diabetes (
20581827
)
Protein-Protein Interactions
42 interactors:
CAPNS1
CCDC184
CD27
CD40
COG7
COMMD3
DGKH
ENOX2
GORASP2
LTBR
MAP3K14
MAP3K5
MAVS
MDM2
NGFRAP1
NMI
NUMBL
RAD23A
RIPK1
RIPK2
RNF111
SDCBP
SEC13
SERPINB9
TDP2
THAP1
TNFRSF11A
TNFRSF12A
TNFRSF13B
TNFRSF14
TNFRSF19
TNFRSF4
TNFRSF8
TRAF2
TRAF3
TRAF3IP2
TRAF6
TRIM27
TRIM37
TRIM8
USP7
ZFAND6
6 interactors:
CDC34
DNM2
PKN1
TRAF2
TRAF5
UBC
Entrez ID
7188
54469
HPRD ID
03834
18314
Ensembl ID
ENSG00000082512
ENSG00000086666
Uniprot IDs
D3DT93
O00463
Q6FIF0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Programmed Cell Death
Cell Death
Death
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of JNK Cascade
Cellular Response To Stimulus
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Immune System Process
Regulation Of Protein Metabolic Process
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Signal Transduction
Regulation Of JNK Cascade
Immune Response
Signal Transduction
Apoptotic Process
Regulation Of Stress-activated MAPK Cascade
Response To Tumor Necrosis Factor
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cellular Protein Metabolic Process
Signaling
Positive Regulation Of MAPK Cascade
Cell Communication
Cellular Response To Organic Substance
Regulation Of Apoptotic Process
Response To Stimulus
Positive Regulation Of Phosphorylation
Regulation Of Intracellular Signal Transduction
Regulation Of Cytokine Production
Response To Cytokine
Regulation Of Phosphorylation
Regulation Of Cell Death
Cellular Response To Cytokine Stimulus
Positive Regulation Of MAP Kinase Activity
Cytokine-mediated Signaling Pathway
Cell Surface Receptor Signaling Pathway
Regulation Of MAPK Cascade
Response To Organic Substance
Regulation Of Immunoglobulin Secretion
Positive Regulation Of Protein Metabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Immune System Process
Regulation Of Lymphocyte Activation
Defense Response
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Ubiquitination
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cell Death
Regulation Of Cell Death
Protein Polyubiquitination
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of MAP Kinase Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of MAPK Cascade
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Toll-like Receptor 4 Signaling Pathway
Regulation Of JUN Kinase Activity
JNK Cascade
Regulation Of Signaling
Positive Regulation Of Transferase Activity
Cellular Protein Modification Process
Toll-like Receptor Signaling Pathway
Protein Catabolic Process
Regulation Of MAPK Cascade
Stress-activated MAPK Cascade
G2/M Transition Of Mitotic Cell Cycle
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of JNK Cascade
Mitotic Cell Cycle Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Negative Regulation Of Membrane Tubulation
Positive Regulation Of Protein Phosphorylation
Activation Of MAPK Activity
Tagcloud
?
adhesion
affinity
bind
cd40
cd40ct
cytoplasmic
dispensable
dominantly
extensive
icam
ikappabalpha
implicated
incapable
intercellular
jak3
kappab
mediators
molecule
much
mutants
necrosis
residues
strongly
tail
traf2
traf3
traf6
transduction
Tagcloud (Difference)
?
adhesion
affinity
bind
cd40
cd40ct
cytoplasmic
dispensable
dominantly
extensive
icam
ikappabalpha
implicated
incapable
intercellular
jak3
kappab
mediators
molecule
much
mutants
necrosis
residues
strongly
tail
traf2
traf3
traf6
transduction
Tagcloud (Intersection)
?