TRAF5 and GORASP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRAF5	GORASP2
Gene Name		TNF receptor-associated factor 5	golgi reassembly stacking protein 2, 55kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Signal Transducer Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding	Protein Binding
	Biological Process	Apoptotic Process Signal Transduction Positive Regulation Of Cell Proliferation Protein Ubiquitination Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Mitotic Cell Cycle Organelle Organization
Pathways			Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Protein-Protein Interactions		42 interactors: CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GORASP2 LTBR MAP3K14 MAP3K5 MAVS MDM2 NGFRAP1 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 USP7 ZFAND6	69 interactors: AAMDC ACY3 AES APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148
Entrez ID		7188	26003
HPRD ID		03834	08303
Ensembl ID		ENSG00000082512	ENSG00000115806
Uniprot IDs		D3DT93 O00463	B4DKT0 B4DNR1 Q9H8Y8
PDB IDs			3RLE 4EDJ
Enriched GO Terms of Interacting Partners?		Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Programmed Cell Death Cell Death Death Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of JNK Cascade Cellular Response To Stimulus Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune System Process Regulation Of Protein Metabolic Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of Signal Transduction Regulation Of JNK Cascade Immune Response Signal Transduction Apoptotic Process Regulation Of Stress-activated MAPK Cascade Response To Tumor Necrosis Factor Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cellular Protein Metabolic Process Signaling Positive Regulation Of MAPK Cascade Cell Communication Cellular Response To Organic Substance Regulation Of Apoptotic Process Response To Stimulus Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Regulation Of Cytokine Production Response To Cytokine Regulation Of Phosphorylation Regulation Of Cell Death Cellular Response To Cytokine Stimulus Positive Regulation Of MAP Kinase Activity Cytokine-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of MAPK Cascade Response To Organic Substance Regulation Of Immunoglobulin Secretion Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Immune System Process Regulation Of Lymphocyte Activation Defense Response Positive Regulation Of Protein Serine/threonine Kinase Activity	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Golgi Organization Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of MAP Kinase Activity Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cargo Loading Into Vesicle Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Protein Transport Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Establishment Of Protein Localization Intracellular Protein Transport Regulation Of Protein Homodimerization Activity Regulation Of MAPK Cascade TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway COPII-coated Vesicle Budding Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor 3 Signaling Pathway Establishment Of Localization In Cell Regulation Of Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Protein Complex Assembly Positive Regulation Of Protein Metabolic Process Protein Homooligomerization Toll-like Receptor 4 Signaling Pathway Cell Death Death Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Positive Regulation Of Transferase Activity Cellular Localization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Protein Ubiquitination Intracellular Transport Negative Regulation Of Programmed Cell Death Negative Regulation Of Transferase Activity Protein Oligomerization Endomembrane System Organization Cell Cycle Cellular Protein Localization
Tagcloud ?		adhesion affinity bind cd40 cd40ct cytoplasmic dispensable dominantly extensive icam ikappabalpha implicated incapable intercellular jak3 kappab mediators molecule much mutants necrosis residues strongly tail traf2 traf3 traf6 transduction
Tagcloud (Difference) ?		adhesion affinity bind cd40 cd40ct cytoplasmic dispensable dominantly extensive icam ikappabalpha implicated incapable intercellular jak3 kappab mediators molecule much mutants necrosis residues strongly tail traf2 traf3 traf6 transduction
Tagcloud (Intersection) ?