THAP1 and PPIG

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		THAP1	PPIG
Description		THAP domain containing 1	peptidylprolyl isomerase G
Image
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Isomerase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle	Protein Folding RNA Splicing
Pathways			mRNA Splicing - Major Pathway SARS-CoV-1 activates/modulates innate immune responses
Drugs			Proline
Diseases		Primary torsion dystonia (PTD)
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		105 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BEND7 BMS1P1 BYSL C1orf216 C1orf35 CDC37 CDKN2D CHD2 CHLSN CSNK2A1 DCAF8 DRC4 DVL2 FAM124A FAM133A FAM9A FGF10 FGF11 FGF12 FXR2 GPATCH2L HNRNPLL HYPK INO80B KANK2 KLF12 KRTAP10-7 L3MBTL2 LASP1 LMNB2 LMO3 LNX1 METTL13 MFAP1 MIS18A MORF4L1 MORF4L2 MRPL11 MRPL53 NDUFAB1 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PHF19 PID1 PNKP POLR2L POLR2M POU6F2 PPIG PRKAA1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RAD54L2 RALY RALYL RBM10 RBM39 RIPPLY1 RNF4 RP9P RPL22 RPS25 SAP30BP SERF2 SLU7 SPANXN2 SPMIP2 SREK1IP1 STRBP TCEA2 TCEANC TPM3 TRAF5 TRIM26 TRIP10 TTLL10 TXN2 U2AF2 UBE2I VCX2 WT1 YES1 ZBTB48 ZCCHC10 ZGPAT ZNF385C ZNF408 ZNF526	26 interacting genes: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RNF10 SLU7 SMN1 SMN2 SP1 TFCP2 THAP1 TRIM54 YWHAG ZCCHC10
Entrez ID		55145	9360
HPRD ID		15496	12083
Ensembl ID		ENSG00000131931	ENSG00000138398
Uniprot IDs		Q9NVV9	Q13427
PDB IDs		2JTG 2KO0 2L1G	2GW2 2WFI 2WFJ 5YZG
Enriched GO Terms of Interacting Partners?		Nucleus RNA Splicing Nucleic Acid Binding RNA Binding Protein Binding MRNA Processing Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process PTB Domain Binding ESC/E(Z) Complex Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Metabolic Process Positive Regulation Of Fat Cell Proliferation	MRNA Metabolic Process RNA Splicing RNA Splicing, Via Transesterification Reactions RNA Metabolic Process MRNA Processing DNA-templated Transcription Termination Z Disc Nucleus Nucleic Acid Metabolic Process SMN Complex Gemini Of Cajal Bodies Spliceosomal Complex Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Biosynthetic Process Cytoplasmic Ribonucleoprotein Granule SMN-Sm Protein Complex RNA Binding Nuclear Speck Transcription Cis-regulatory Region Binding DNA Binding Nucleoplasm Protein Binding Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Second Spliceosomal Transesterification Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?