THAP1 and RPS25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP1	RPS25
Gene Name		THAP domain containing, apoptosis associated protein 1	ribosomal protein S25
Image
Gene Ontology Annotations	Cellular Component	Nucleus PML Body	Nucleus Nucleolus Cytoplasm Cytosol Ribosome Small Ribosomal Subunit Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408	5 interactors: APP HAP1 SGSM2 THAP1 UPF2
Entrez ID		55145	6230
HPRD ID		15496	01593
Ensembl ID		ENSG00000131931
Uniprot IDs		Q9NVV9	P62851
PDB IDs		2JTG 2KO0 2L1G	3J3A
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process	Axon Cargo Transport Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Intracellular Transport Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Establishment Of Localization In Cell Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Synaptic Growth At Neuromuscular Junction Cellular Localization Regulation Of Cell Cycle Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Collateral Sprouting In Absence Of Injury Positive Regulation Of Cilium Assembly Late Endosome To Golgi Transport Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Cell Cycle RNA Metabolic Process Microtubule-based Movement Hypothalamus Cell Differentiation Neuron Remodeling Exocytosis Gene Expression Vesicle-mediated Transport Negative Regulation Of Beta-amyloid Formation Retrograde Axon Cargo Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Response To Oxidative Stress Positive Regulation Of Synaptic Transmission, GABAergic Forebrain Development Aromatic Compound Catabolic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration Posttranscriptional Regulation Of Gene Expression DNA Demethylation
Tagcloud ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Difference) ?		assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Intersection) ?