THAP1 and ZCCHC10

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		THAP1	ZCCHC10
Description		THAP domain containing 1	zinc finger CCHC-type containing 10
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240)	Eyebrow thickness ( 26926045)
Interacting Genes		105 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BEND7 BMS1P1 BYSL C1orf216 C1orf35 CDC37 CDKN2D CHD2 CHLSN CSNK2A1 DCAF8 DRC4 DVL2 FAM124A FAM133A FAM9A FGF10 FGF11 FGF12 FXR2 GPATCH2L HNRNPLL HYPK INO80B KANK2 KLF12 KRTAP10-7 L3MBTL2 LASP1 LMNB2 LMO3 LNX1 METTL13 MFAP1 MIS18A MORF4L1 MORF4L2 MRPL11 MRPL53 NDUFAB1 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PHF19 PID1 PNKP POLR2L POLR2M POU6F2 PPIG PRKAA1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RAD54L2 RALY RALYL RBM10 RBM39 RIPPLY1 RNF4 RP9P RPL22 RPS25 SAP30BP SERF2 SLU7 SPANXN2 SPMIP2 SREK1IP1 STRBP TCEA2 TCEANC TPM3 TRAF5 TRIM26 TRIP10 TTLL10 TXN2 U2AF2 UBE2I VCX2 WT1 YES1 ZBTB48 ZCCHC10 ZGPAT ZNF385C ZNF408 ZNF526	55 interacting genes: ANKRD36B ARGLU1 BEND7 CAVIN1 CEP63 CEP70 COIL CTNNBL1 DAB1 DPPA2 DZIP3 EEF1A1 ELOA2 EPB41 FAM9B FRA10AC1 GKAP1 HMGXB4 IK KCTD6 KPNA3 LNX1 LUC7L2 MAB21L3 MEOX1 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 RPL22 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A
Entrez ID		55145	54819
HPRD ID		15496	15699
Ensembl ID		ENSG00000131931	ENSG00000155329
Uniprot IDs		Q9NVV9	B3KVL5 B4DU89 D6R9G7 D6RHC2 G3XAM1 Q8TBK6
PDB IDs		2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		Nucleus RNA Splicing Nucleic Acid Binding RNA Binding Protein Binding MRNA Processing Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process PTB Domain Binding ESC/E(Z) Complex Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Metabolic Process Positive Regulation Of Fat Cell Proliferation	RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Processing Spliceosomal Complex Nucleoplasm Nuclear Speck RNA Metabolic Process RNA Processing Protein-RNA Complex Assembly Nucleus Precatalytic Spliceosome Nucleic Acid Metabolic Process RNA Binding U2-type Prespliceosome Assembly Protein Binding Identical Protein Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process U1 SnRNP Cajal Body U12-type Spliceosomal Complex U2-type Spliceosomal Complex Protein-containing Complex Assembly Pre-mRNA 3'-splice Site Binding RS Domain Binding U4/U6 X U5 Tri-snRNP Complex Cytosol Protein-containing Complex Organization MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Small Nuclear Ribonucleoprotein Complex MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome
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