Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TNNC1 and TRIM63
Number of citations of the paper that reports this interaction (PMID
15601779
)
57
Data Source:
BioGRID
(enzymatic study)
TNNC1
TRIM63
Gene Name
troponin C type 1 (slow)
tripartite motif containing 63, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mitochondrion
Cytosol
Troponin Complex
Actin Cytoskeleton
Nucleus
Cytoplasm
Microtubule
Z Disc
M Band
Molecular Function
Calcium Ion Binding
Protein Binding
Troponin I Binding
Troponin T Binding
Protein Homodimerization Activity
Calcium-dependent Protein Binding
Actin Filament Binding
Ubiquitin-protein Transferase Activity
Signal Transducer Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Titin Binding
Biological Process
Diaphragm Contraction
Regulation Of Muscle Contraction
Response To Metal Ion
Muscle Filament Sliding
Regulation Of Muscle Filament Sliding Speed
Regulation Of ATPase Activity
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Contraction
Muscle Contraction
Signal Transduction
Regulation Of Gene Expression
Skeletal Muscle Atrophy
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Interleukin-1
Cellular Response To Dexamethasone Stimulus
Pathways
Striated Muscle Contraction
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Trifluoperazine
Levosimendan
Felodipine
Bepridil
Calcium
Dihydroxyaluminium
5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-Protein Interactions
11 interactors:
CDK1
POLR2G
RBM15B
TCP10L
TNNI1
TNNI2
TNNI3
TNNT1
TNNT2
TRIM63
UBE2C
87 interactors:
ACTA1
AK1
AKR7A2
ALDOA
ANKRD1
APP
ATP5B
ATXN3
ATXN3L
BAP1
CKB
CKM
DCAF6
DES
EEF1G
EHHADH
EIF3E
ENO3
ESPL1
FHL2
FLNC
GFM1
GMEB1
HIBADH
JOSD1
LMCD1
MRPL19
MRPL41
MYBPC1
MYBPC3
MYL2
MYOT
MYOZ1
NDUFA1
NEB
NEBL
NOMO1
NRAP
OTUB1
OTUB2
PDHB
PDK4
PIAS1
PIAS2
PIAS3
PKM
PSMD4
PYGM
SENP2
SENP3
SQSTM1
SRF
STAM
SUMO2
TCAP
TNNC1
TNNI1
TNNI2
TNNI3
TNNT1
TNNT3
TRIM54
TRIM55
TTN
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2I
UBE2J1
UBE2U
UCHL1
UCHL3
UCHL5
UQCRC1
USP13
USP15
USP2
USP21
USP28
USP33
USP4
USP5
USP7
USP8
UXT
YOD1
Entrez ID
7134
84676
HPRD ID
08930
05843
Ensembl ID
ENSG00000114854
ENSG00000158022
Uniprot IDs
P63316
Q6FH91
B4DN95
Q969Q1
PDB IDs
1AP4
1IH0
1J1D
1J1E
1LXF
1MXL
1OZS
1SPY
1WRK
1WRL
2JT0
2JT3
2JT8
2JTZ
2JXL
2KDH
2KFX
2KGB
2KRD
2L1R
2L98
3RV5
3SD6
3SWB
4GJE
4GJF
4GJG
2D8U
3DDT
Enriched GO Terms of Interacting Partners
?
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle Contraction
Muscle System Process
Regulation Of Muscle Contraction
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Ventricular Cardiac Muscle Tissue Development
Cardiac Muscle Tissue Morphogenesis
Muscle Tissue Morphogenesis
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Negative Regulation Of ATPase Activity
Actin Filament-based Process
Striated Muscle Contraction
Striated Muscle Tissue Development
Muscle Tissue Development
Cardiac Ventricle Development
Movement Of Cell Or Subcellular Component
Cardiac Chamber Development
Muscle Structure Development
Heart Development
Skeletal Muscle Contraction
Heart Morphogenesis
Regulation Of ATPase Activity
Musculoskeletal Movement
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Muscle Organ Development
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Cellular Macromolecule Catabolic Process
Cardiovascular System Development
Pronuclear Fusion
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of MRNA Processing
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Metabolic Process
Free Ubiquitin Chain Polymerization
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Positive Regulation Of Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Protein Modification By Small Protein Removal
Muscle Filament Sliding
Actin-myosin Filament Sliding
Protein Deubiquitination
Actin-mediated Cell Contraction
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Actin Filament-based Movement
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Proteolysis
Muscle Contraction
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Muscle System Process
Regulation Of Protein Catabolic Process
Actin Filament-based Process
Protein K63-linked Deubiquitination
Striated Muscle Cell Development
Striated Muscle Contraction
Muscle Cell Development
Muscle Structure Development
Myofibril Assembly
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Proteolysis
Cardiac Muscle Tissue Morphogenesis
Striated Muscle Cell Differentiation
Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Muscle Organ Morphogenesis
Actomyosin Structure Organization
Protein Sumoylation
Protein Metabolic Process
Striated Muscle Tissue Development
Muscle Cell Differentiation
Muscle Tissue Development
Regulation Of Muscle Contraction
Protein Modification By Small Protein Conjugation
Muscle Organ Development
Heart Morphogenesis
Regulation Of Cellular Protein Metabolic Process
Cardiac Myofibril Assembly
Muscle Fiber Development
Monoubiquitinated Protein Deubiquitination
Tagcloud
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Difference)
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Intersection)
?