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TNNC1 and TNNT1
Number of citations of the paper that reports this interaction (PMID
9448267
)
8
Data Source:
BioGRID
(two hybrid)
HPRD
(in vitro, two hybrid)
TNNC1
TNNT1
Gene Name
troponin C type 1 (slow)
troponin T type 1 (skeletal, slow)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mitochondrion
Cytosol
Troponin Complex
Actin Cytoskeleton
Cytosol
Troponin Complex
Molecular Function
Calcium Ion Binding
Protein Binding
Troponin I Binding
Troponin T Binding
Protein Homodimerization Activity
Calcium-dependent Protein Binding
Actin Filament Binding
Tropomyosin Binding
Troponin T Binding
Biological Process
Diaphragm Contraction
Regulation Of Muscle Contraction
Response To Metal Ion
Muscle Filament Sliding
Regulation Of Muscle Filament Sliding Speed
Regulation Of ATPase Activity
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Contraction
Skeletal Muscle Contraction
Muscle Filament Sliding
Slow-twitch Skeletal Muscle Fiber Contraction
Negative Regulation Of Muscle Contraction
Pathways
Striated Muscle Contraction
Striated Muscle Contraction
Drugs
Trifluoperazine
Levosimendan
Felodipine
Bepridil
Calcium
Dihydroxyaluminium
5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-Protein Interactions
11 interactors:
CDK1
POLR2G
RBM15B
TCP10L
TNNI1
TNNI2
TNNI3
TNNT1
TNNT2
TRIM63
UBE2C
61 interactors:
ARMC8
BLOC1S2
BMPR1B
C2orf44
CCDC136
CCDC85B
CHD3
DDX5
EEF1G
FAF1
FXR2
FYN
HAP1
HMGXB4
HMP19
HSP90AB1
IMMT
KAT5
KRT40
LARP1
LDOC1
MARS
MORF4L1
NACAD
NAGK
NFE2L2
NINL
OSBP2
OSM
PI4KA
PLEKHF1
PNMA1
PPFIA1
PRKG1
PSMC5
SEC31A
SERPINA4
SH3GL3
SMAD1
SMAD2
SMURF1
SNW1
TBPL1
TFIP11
TGFBR1
TMEM98
TNNC1
TNNI1
TNNI2
TNNI3
TPM1
TPM3
TRA2A
TRIM63
UBE2D1
VIM
ZC3H15
ZKSCAN5
ZMYND19
ZNF250
ZNF768
Entrez ID
7134
7138
HPRD ID
08930
01841
Ensembl ID
ENSG00000114854
ENSG00000105048
Uniprot IDs
P63316
Q6FH91
P13805
PDB IDs
1AP4
1IH0
1J1D
1J1E
1LXF
1MXL
1OZS
1SPY
1WRK
1WRL
2JT0
2JT3
2JT8
2JTZ
2JXL
2KDH
2KFX
2KGB
2KRD
2L1R
2L98
3RV5
3SD6
3SWB
4GJE
4GJF
4GJG
Enriched GO Terms of Interacting Partners
?
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle Contraction
Muscle System Process
Regulation Of Muscle Contraction
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Ventricular Cardiac Muscle Tissue Development
Cardiac Muscle Tissue Morphogenesis
Muscle Tissue Morphogenesis
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Negative Regulation Of ATPase Activity
Actin Filament-based Process
Striated Muscle Contraction
Striated Muscle Tissue Development
Muscle Tissue Development
Cardiac Ventricle Development
Movement Of Cell Or Subcellular Component
Cardiac Chamber Development
Muscle Structure Development
Heart Development
Skeletal Muscle Contraction
Heart Morphogenesis
Regulation Of ATPase Activity
Musculoskeletal Movement
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Muscle Organ Development
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Cellular Macromolecule Catabolic Process
Cardiovascular System Development
Pronuclear Fusion
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of MRNA Processing
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Metabolic Process
Free Ubiquitin Chain Polymerization
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Positive Regulation Of Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Muscle Filament Sliding
Actin-myosin Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle System Process
Regulation Of Metabolic Process
Muscle Contraction
Regulation Of Gene Expression
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Muscle Contraction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Ventricular Cardiac Muscle Tissue Morphogenesis
Movement Of Cell Or Subcellular Component
Ventricular Cardiac Muscle Tissue Development
Regulation Of Cellular Process
Cardiac Muscle Tissue Morphogenesis
Signal Transduction
Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Gene Expression
Cellular Response To Organic Substance
Muscle Tissue Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Regulation Of RNA Metabolic Process
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Cellular Macromolecule Biosynthetic Process
BMP Signaling Pathway
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Signaling
Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Striated Muscle Contraction
Positive Regulation Of Cellular Biosynthetic Process
Cell Communication
Cellular Response To Transforming Growth Factor Beta Stimulus
RNA Metabolic Process
RNA Biosynthetic Process
Response To Transforming Growth Factor Beta
Cardiac Muscle Tissue Development
Primary MiRNA Processing
Cellular Response To Stimulus
Regulation Of Cellular Component Organization
Positive Regulation Of Apoptotic Signaling Pathway
Response To Stimulus
Tagcloud
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
prkcg
psg1
pw39
Tagcloud (Difference)
?
apoc2
atp1a3
bckdha
cgb
cgm2
cyp2a
d19s112
d19s116
d19s117
d19s118
d19s119
d19s19
d19s2
d19s37
d19s50
d19s51
d19s54
d19s55
d19s6
d19s62
d19s63
d19s7
d19s8
d19s9
manb
pepd
prkcg
psg1
pw39
Tagcloud (Intersection)
?