TNNC1 and RBM15B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TNNC1	RBM15B
Gene Name		troponin C type 1 (slow)	RNA binding motif protein 15B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Troponin Complex Actin Cytoskeleton	Nucleoplasm Nucleolus
	Molecular Function	Calcium Ion Binding Protein Binding Troponin I Binding Troponin T Binding Protein Homodimerization Activity Calcium-dependent Protein Binding Actin Filament Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Diaphragm Contraction Regulation Of Muscle Contraction Response To Metal Ion Muscle Filament Sliding Regulation Of Muscle Filament Sliding Speed Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Regulation Of Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated MRNA Processing Nucleocytoplasmic Transport RNA Splicing Viral Process Negative Regulation Of Transcription, DNA-templated
Pathways		Striated Muscle Contraction
Drugs		Trifluoperazine Levosimendan Felodipine Bepridil Calcium Dihydroxyaluminium 5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		11 interactors: CDK1 POLR2G RBM15B TCP10L TNNI1 TNNI2 TNNI3 TNNT1 TNNT2 TRIM63 UBE2C	6 interactors: ATP6V0D2 CDC23 EGR2 NAV2 NXF1 TNNC1
Entrez ID		7134	29890
HPRD ID		08930	11486
Ensembl ID		ENSG00000114854	ENSG00000179837
Uniprot IDs		P63316 Q6FH91	Q8NDT2
PDB IDs		1AP4 1IH0 1J1D 1J1E 1LXF 1MXL 1OZS 1SPY 1WRK 1WRL 2JT0 2JT3 2JT8 2JTZ 2JXL 2KDH 2KFX 2KGB 2KRD 2L1R 2L98 3RV5 3SD6 3SWB 4GJE 4GJF 4GJG
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle Contraction Muscle System Process Regulation Of Muscle Contraction Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Tissue Development Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Negative Regulation Of ATPase Activity Actin Filament-based Process Striated Muscle Contraction Striated Muscle Tissue Development Muscle Tissue Development Cardiac Ventricle Development Movement Of Cell Or Subcellular Component Cardiac Chamber Development Muscle Structure Development Heart Development Skeletal Muscle Contraction Heart Morphogenesis Regulation Of ATPase Activity Musculoskeletal Movement Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Muscle Organ Development Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Macromolecule Catabolic Process Cardiovascular System Development Pronuclear Fusion Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of MRNA Processing Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Metabolic Process Free Ubiquitin Chain Polymerization Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Positive Regulation Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Ubiquitination	Parasympathetic Nervous System Development Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Autonomic Nervous System Development Cranial Nerve Development Nerve Development Regulation Of Systemic Arterial Blood Pressure Rhombomere 5 Formation Rhombomere 3 Formation Regulation Of Muscle Filament Sliding Speed Nuclear Export Rhombomere 3 Morphogenesis Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Brain Segmentation Regulation Of Muscle Filament Sliding Vagus Nerve Development Regulation Of Blood Pressure Diaphragm Contraction Rhombomere 3 Development Rhombomere 5 Development Rhombomere Morphogenesis Involuntary Skeletal Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Glossopharyngeal Nerve Development Nucleocytoplasmic Transport Nuclear Transport Muscle Organ Development Negative Regulation Of ATPase Activity Metaphase/anaphase Transition Of Mitotic Cell Cycle Neurological System Process Response To Insulin Poly(A)+ MRNA Export From Nucleus Blood Circulation Striated Muscle Tissue Development Rhombomere Development Muscle Tissue Development Facial Nerve Structural Organization Regulation Of Exit From Mitosis Facial Nerve Morphogenesis Optic Nerve Development Respiratory System Process Cellular Metal Ion Homeostasis Rhythmic Behavior Cellular Cation Homeostasis Cellular Ion Homeostasis Response To Peptide Hormone Anatomical Structure Arrangement Cellular Response To Organonitrogen Compound Metal Ion Homeostasis Protein K11-linked Ubiquitination Response To Peptide
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