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CASP7 and GORASP1
Number of citations of the paper that reports this interaction (PubMedID
11815631
)
43
Data Source:
HPRD
(in vitro, in vivo)
CASP7
GORASP1
Description
caspase 7
golgi reassembly stacking protein 1
Image
GO Annotations
Cellular Component
Fibrillar Center
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Golgi Membrane
Golgi Apparatus
Cis-Golgi Network
Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Molecular Function
RNA Binding
Catalytic Activity
Aspartic-type Endopeptidase Activity
Cysteine-type Endopeptidase Activity
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Hydrolase Activity
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Plasma Membrane Repair
Regulation Of Transcription By RNA Polymerase II
Proteolysis
Apoptotic Process
Heart Development
Response To UV
Protein Processing
Protein Catabolic Process
Defense Response To Bacterium
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Neuron Apoptotic Process
Fibroblast Apoptotic Process
Ceramide Biosynthetic Process
Striated Muscle Cell Differentiation
Neuron Apoptotic Process
Protein Maturation
Protein Poly-ADP-ribosylation
Lymphocyte Apoptotic Process
Pyroptotic Inflammatory Response
Cellular Response To Lipopolysaccharide
Leukocyte Apoptotic Process
Cellular Response To Staurosporine
Execution Phase Of Apoptosis
Positive Regulation Of Plasma Membrane Repair
Protein N-linked Glycosylation
Golgi Organization
Protein Transport
Negative Regulation Of Dendrite Morphogenesis
Establishment Of Protein Localization To Plasma Membrane
Golgi Ribbon Formation
Pathways
Activation of caspases through apoptosome-mediated cleavage
SMAC (DIABLO) binds to IAPs
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
Apoptotic cleavage of cellular proteins
SMAC, XIAP-regulated apoptotic response
Caspase-mediated cleavage of cytoskeletal proteins
Golgi Cisternae Pericentriolar Stack Reorganization
Golgi Cisternae Pericentriolar Stack Reorganization
COPII-mediated vesicle transport
COPI-mediated anterograde transport
Drugs
Fica
Emricasan
Incadronic acid
Diseases
GWAS
Cataracts (
34127677
)
Smoking status (ever vs never smokers) (
30643258
)
Vitiligo (
22561518
27723757
)
Social communication problems (
24564958
)
Interacting Genes
63 interacting genes:
AR
ARHGDIA
BIRC2
BIRC3
BIRC5
BIRC7
CASP10
CASP2
CASP3
CASP8
CASP9
CAST
CDC42
CFLAR
CLSPN
COPS6
CTSG
DCTN1
DFFA
DSP
EIF2AK2
GOLGA3
GORASP1
GZMB
HNRNPH1
HSPA5
KRT18
LYN
MAGEA11
MAPT
MAX
MEF2A
MEF2D
NEDD4
NIF3L1
PARP1
PLA2G4B
PRKCZ
PSEN1
PSEN2
PSIP1
PSME3
PTGES3
PTMA
RAC1
RAD21
RAD51
RASA1
RB1
RNF7
ROCK1
SAT1
SP1
SPTAN1
SRF
STAT1
STK24
TERF1
TNFRSF1A
TRIM25
UBE4B
VIM
XIAP
17 interacting genes:
AGPS
CASP3
CASP7
CDK1
GOLGA2
HIPK3
LONRF1
MAPK6
NEFL
PLK1
PRKD2
RPS6KA1
SCRN1
TGFA
TMED2
TMED3
TRAF4
Entrez ID
840
64689
HPRD ID
03457
06038
Ensembl ID
ENSG00000165806
ENSG00000114745
Uniprot IDs
A0A0A0MRL7
B4DWA2
P55210
A0A8Q3SHU6
A0A8Q3WL08
B3KPY8
B4E1H8
Q9BQQ3
PDB IDs
1F1J
1GQF
1I4O
1I51
1K86
1K88
1KMC
1SHJ
1SHL
2QL5
2QL7
2QL9
2QLB
2QLF
2QLJ
3EDR
3H1P
3IBC
3IBF
3R5K
4FDL
4FEA
4HQ0
4HQR
4JB8
4JJ8
4JR1
4JR2
4LSZ
4ZVO
4ZVP
4ZVQ
4ZVR
4ZVS
4ZVT
4ZVU
5IC6
5K20
5V6U
5V6Z
7WZS
8DGZ
8DJ3
4REY
6G8T
6G8W
Enriched GO Terms of Interacting Partners
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Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Apoptotic Process
Programmed Cell Death
Cell Death
Cytosol
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Apoptotic Process
Nucleus
Cytoplasm
Intracellular Signal Transduction
Enzyme Binding
Regulation Of Primary Metabolic Process
Negative Regulation Of Cellular Component Organization
Protein-containing Complex
Positive Regulation Of Macromolecule Metabolic Process
Response To Stress
Execution Phase Of Apoptosis
Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Neuron Apoptotic Process
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Regulation Of Cellular Component Organization
Regulation Of Metabolic Process
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Signal Transduction
Cellular Response To Stress
Myeloid Cell Differentiation
Positive Regulation Of Signal Transduction
Positive Regulation Of Signaling
Regulation Of Protein-containing Complex Assembly
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Necroptotic Process
Protein Metabolic Process
Cysteine-type Endopeptidase Activity
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Proteolysis
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of Cell Communication
Protein Maturation
Regulation Of Programmed Necrotic Cell Death
Regulation Of Canonical NF-kappaB Signal Transduction
Apoptotic Signaling Pathway
Regulation Of Protein Metabolic Process
DNA-binding Transcription Factor Binding
Protein Processing
Protein Serine Kinase Activity
Golgi Organization
Protein Phosphorylation
Phosphorylation
Protein Serine/threonine Kinase Activity
Regulation Of Synaptic Vesicle Cycle
Protein Kinase Activity
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Kinase Activity
Protein Modification Process
Cellular Response To Staurosporine
COPII-coated ER To Golgi Transport Vesicle
Regulation Of Apoptotic Process
Golgi Disassembly
Regulation Of Programmed Cell Death
Centrosome Cycle
Hepatocyte Proliferation
G2/M Transition Of Mitotic Cell Cycle
Protein Metabolic Process
Cell Cycle G2/M Phase Transition
Potassium Channel Inhibitor Activity
Golgi Cisterna Membrane
Fibroblast Apoptotic Process
Mitotic Nuclear Membrane Disassembly
Transferase Activity
Intracellular Signal Transduction
Nuclear Membrane Disassembly
Microtubule Organizing Center Organization
Membrane Disassembly
COPI-coated Vesicle Membrane
Protein Kinase Binding
Cytoplasm
Protein Poly-ADP-ribosylation
Aspartic-type Endopeptidase Activity
Neuron Apoptotic Process
Peptidyl-threonine Phosphorylation
Execution Phase Of Apoptosis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Protein Localization To Site Of Double-strand Break
Microtubule Cytoskeleton Organization Involved In Mitosis
Apoptotic Process
Programmed Cell Death
Cell Death
Mitotic Cell Cycle Phase Transition
Mitotic G2 DNA Damage Checkpoint Signaling
Phosphate-containing Compound Metabolic Process
Cellular Response To Alkaloid
ATP Binding
Chromosome Condensation
Cell Cycle Phase Transition
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Tagcloud (Difference)
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Tagcloud (Intersection)
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