BTK and PLCG1

  • Number of citations of the paper that reports this interaction (PMID 15184383)
  • 18
  • Data Source:
  • HPRD (in vitro)

BTK

PLCG1

Gene Name Bruton agammaglobulinemia tyrosine kinase phospholipase C, gamma 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 64 interactors: ABL1 APP ARHGAP17 ARID3A ARRB1 BCL2L11 BLNK BMX CAV1 CBL CD19 CMTM3 DAPP1 EWSR1 FAS FASLG FYN GNA12 GNAQ GNG2 GTF2I HCK IBTK IRAK1 ITK JAK1 KHDRBS1 KIT LYN MYD88 PIK3AP1 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLAU PLCG1 PLCG2 PRKCA PRKCB PRKCE PRKCQ PRKCZ PRKD1 RELA RPS6KB1 RPS6KB2 SH2B2 SH3BP5 STAT5A SYK TEC TIRAP TLR4 TLR6 TLR8 TLR9 TNFRSF10A TP53 VAV1 WAS WASF2 106 interactors: ABL1 AGAP2 AGTR1 AKT1 ALK ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GNB2L1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PTK2 PTPN11 PTPRJ RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 695 5335
HPRD ID 02248 01398
Ensembl ID ENSG00000010671 ENSG00000124181
Uniprot IDs Q06187 Q5JY90 P19174 Q4LE43 Q9UFY1
PDB IDs 1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P 3GEN 3K54 3OCS 3OCT 3P08 3PIX 3PIY 3PIZ 3PJ1 3PJ2 3PJ3 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Difference) ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
Tagcloud (Intersection) ?