BTK and FYN

  • Number of citations of the paper that reports this interaction (PMID 8058772)
  • 33

BTK

FYN

Gene Name Bruton agammaglobulinemia tyrosine kinase FYN proto-oncogene, Src family tyrosine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 64 interactors: ABL1 APP ARHGAP17 ARID3A ARRB1 BCL2L11 BLNK BMX CAV1 CBL CD19 CMTM3 DAPP1 EWSR1 FAS FASLG FYN GNA12 GNAQ GNG2 GTF2I HCK IBTK IRAK1 ITK JAK1 KHDRBS1 KIT LYN MYD88 PIK3AP1 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLAU PLCG1 PLCG2 PRKCA PRKCB PRKCE PRKCQ PRKCZ PRKD1 RELA RPS6KB1 RPS6KB2 SH2B2 SH3BP5 STAT5A SYK TEC TIRAP TLR4 TLR6 TLR8 TLR9 TNFRSF10A TP53 VAV1 WAS WASF2 182 interactors: ACP1 ADAM15 ADD2 ARHGAP32 ARHGAP33 ATXN1 BCAR1 BCL3 BTK C7orf25 C8orf33 CASP3 CASP8 CAV1 CBL CBLB CBLC CD19 CD2 CD226 CD247 CD2AP CD36 CD44 CD48 CD5 CD55 CD79A CD79B CDH1 CDK1 CDK5 CLTC CMA1 CNN1 CNN3 CNTN1 CNTNAP1 CRK CSF1R CSF2RB CSK CTLA4 CTNNB1 CTNND2 DAG1 DLG4 DOK1 DOK3 DOK4 EFS ENO1 EPHA3 EPHA4 EPHA8 EPHB3 EVL FAS FASLG FCER2 FCGR2A FLOT1 FLOT2 FLT1 FNBP4 FYB GAB3 GNB2L1 GP6 GRAP GRB10 GRB2 GRIN1 GRIN2A GRIN2B HNRNPK HRAS HSP90AA1 HTR6 IL1B IL2RB IL7R IRS1 ITCH ITGB4 ITK ITPR1 JAK2 JUP KDM1A KDR KHDRBS1 KIT LAT LCP2 MAG MAP2 MAPT MCAM MED28 MS4A1 NCAM1 NEDD4 NEDD9 NMT1 NPHS1 NR3C1 NTRK2 PAG1 PAK2 PDE4D PDGFRB PECAM1 PIK3R1 PIK3R2 PLAUR PLCG1 PLCG2 PLD2 PRKCD PRKCE PRKCH PRKCQ PRKCZ PRMT6 PTK2 PTK2B PTPN11 PTPN5 PTPRA PTPRC PTPRE PTPRF PTPRZ1 PXN RAF1 RPL10 SDC3 SH2B2 SH2D1A SH3BP2 SHC1 SIT1 SKAP1 SKAP2 SLAMF1 SNCA SOCS1 SOS1 SPHK1 SPHK2 SPN STAT1 STAT3 SUV39H1 SYK TCAP THY1 TNF TNK2 TNNT1 TOM1L1 TRAF6 TRAT1 TRPC6 TRPV4 TUBA1B TUBA3C TUBA4A TXK TYK2 TYRO3 UHRF2 UNC119 VAV1 VAV2 WAS WASF1 WASF2 WBP11 YTHDC1 ZAP70
Entrez ID 695 2534
HPRD ID 02248 00655
Ensembl ID ENSG00000010671 ENSG00000010810
Uniprot IDs Q06187 Q5JY90 P06241 Q5R3A8
PDB IDs 1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P 3GEN 3K54 3OCS 3OCT 3P08 3PIX 3PIY 3PIZ 3PJ1 3PJ2 3PJ3 1A0N 1AOT 1AOU 1AVZ 1AZG 1EFN 1FYN 1G83 1M27 1NYF 1NYG 1SHF 1ZBJ 2DQ7 3H0F 3H0H 3H0I 3UA6 3UA7 4D8D 4EIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
293t  analyzing  anchoring  aspartate  binds  coclusters  coexpressed  family  implicated  involves  learning  lyn  mediate  member  nmda  nr2a  participates  plasticity  promotes  psd  ptk  ptks  scaffold  serving  src  substrate  synaptic  tyrosine  yes 
Tagcloud (Difference) ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
293t  analyzing  anchoring  aspartate  binds  coclusters  coexpressed  family  implicated  involves  learning  mediate  member  nmda  nr2a  participates  plasticity  promotes  psd  ptk  ptks  scaffold  serving  src  substrate  synaptic  tyrosine  yes 
Tagcloud (Intersection) ?
lyn