PLCG1 and GAB1

  • Number of citations of the paper that reports this interaction (PMID 8596638)
  • 131
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, far western blotting)
  • HPRD (in vivo)

PLCG1

GAB1

Gene Name phospholipase C, gamma 1 GRB2-associated binding protein 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 106 interactors: ABL1 AGAP2 AGTR1 AKT1 ALK ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GNB2L1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PTK2 PTPN11 PTPRJ RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70 31 interactors: ARHGAP32 C1QBP CRK CRKL EGFR EPOR FRS2 GAB2 GRAP2 GRB2 GTF2A1L INPP5D INSR LAT2 MAP3K3 MAPK1 MAPK3 MAPK4 MARK2 MET MST1R PDGFRB PIK3CG PIK3R1 PLCG1 PLCG2 PTPN11 PTPN18 RET SHC1 SOS1
Entrez ID 5335 2549
HPRD ID 01398 05116
Ensembl ID ENSG00000124181 ENSG00000109458
Uniprot IDs P19174 Q4LE43 Q9UFY1 Q13480 Q9HA84
PDB IDs 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
Tagcloud (Difference) ?
13b  adjusting  associations  card11  clear  consortium  correcting  determinants  endometrioid  eoc  highlight  histologies  histology  immunity  inherited  member  modulating  mucinous  note  phospholipase  rs11696662  rs17250239  rs41324349  rs7501462  serous  superfamily  threshold  tnfrsf13b  traf2 
adaptor  amplifies  antagonism  bdl  bile  binder  broad  ccl5  chemokine  conditional  contributor  duct  elucidate  exacerbated  fibrogenesis  fibrosis  fibrotic  gab1cko  grb2  hepatocyte  hepatocytes  injections  knockout  ligation  lipopolysaccharide  liver  livers  myofibroblasts  tetrachloride 
Tagcloud (Intersection) ?