BTK and PLCG2

  • Number of citations of the paper that reports this interaction (PMID 10981967)
  • 28
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

BTK

PLCG2

Gene Name Bruton agammaglobulinemia tyrosine kinase phospholipase C, gamma 2 (phosphatidylinositol-specific)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 64 interactors: ABL1 APP ARHGAP17 ARID3A ARRB1 BCL2L11 BLNK BMX CAV1 CBL CD19 CMTM3 DAPP1 EWSR1 FAS FASLG FYN GNA12 GNAQ GNG2 GTF2I HCK IBTK IRAK1 ITK JAK1 KHDRBS1 KIT LYN MYD88 PIK3AP1 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLAU PLCG1 PLCG2 PRKCA PRKCB PRKCE PRKCQ PRKCZ PRKD1 RELA RPS6KB1 RPS6KB2 SH2B2 SH3BP5 STAT5A SYK TEC TIRAP TLR4 TLR6 TLR8 TLR9 TNFRSF10A TP53 VAV1 WAS WASF2 34 interactors: BLK BLNK BTK CBLB CD19 DAPP1 EGFR EPOR ERBB2 FCER1G FLT1 FYN GAB1 GAB2 HCK IRS1 ITK JAK1 JAK2 KDR KHDRBS1 LAT LAT2 LCK LCP2 LIME1 LYN NPM1 PRKD1 SH3BP2 SHC1 SYK TEC ZNF512B
Entrez ID 695 5336
HPRD ID 02248 02570
Ensembl ID ENSG00000010671 ENSG00000197943
Uniprot IDs Q06187 Q5JY90 P16885
PDB IDs 1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P 3GEN 3K54 3OCS 3OCT 3P08 3PIX 3PIY 3PIZ 3PJ1 3PJ2 3PJ3 2K2J 2W2W 2W2X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
16x10  associations  chrne  comprehensively  dysregulated  escc  esccs  esophageal  fyn  gc  gcs  germline  gnai3  han  itch  map2k1  map2k4  mapk8  observe  pak4  pik3r3  prlr  rank  resampling  rps6kb2  tln1  validate  warranted  wasl 
Tagcloud (Difference) ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
16x10  associations  chrne  comprehensively  dysregulated  escc  esccs  esophageal  fyn  gc  gcs  germline  gnai3  han  itch  map2k1  map2k4  mapk8  observe  pak4  pik3r3  prlr  rank  resampling  rps6kb2  tln1  validate  warranted  wasl 
Tagcloud (Intersection) ?