BTK and BCL2L11

  • Number of citations of the paper that reports this interaction (PMID 15096481)
  • 7

BTK

BCL2L11

Gene Name Bruton agammaglobulinemia tyrosine kinase BCL2-like 11 (apoptosis facilitator)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic lymphocytic leukemia ( 18758461)
  • Dehydroepiandrosterone sulphate levels ( 21533175)
  • Primary sclerosing cholangitis ( 21151127)
Protein-Protein Interactions 64 interactors: ABL1 APP ARHGAP17 ARID3A ARRB1 BCL2L11 BLNK BMX CAV1 CBL CD19 CMTM3 DAPP1 EWSR1 FAS FASLG FYN GNA12 GNAQ GNG2 GTF2I HCK IBTK IRAK1 ITK JAK1 KHDRBS1 KIT LYN MYD88 PIK3AP1 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLAU PLCG1 PLCG2 PRKCA PRKCB PRKCE PRKCQ PRKCZ PRKD1 RELA RPS6KB1 RPS6KB2 SH2B2 SH3BP5 STAT5A SYK TEC TIRAP TLR4 TLR6 TLR8 TLR9 TNFRSF10A TP53 VAV1 WAS WASF2 26 interactors: AKT1 APP ATP6V1G1 AURKB BCL2 BCL2A1 BCL2L1 BCL2L2 BTK DYNLL1 DYNLL2 FEM1C FGL1 GNB2L1 GTF2I MAGEA11 MAPK10 MAPK8 MAPK9 MCL1 MEX3D RIOK3 SMARCB1 TRIM2 VDAC1 YWHAB
Entrez ID 695 10018
HPRD ID 02248 04828
Ensembl ID ENSG00000010671 ENSG00000153094
Uniprot IDs Q06187 Q5JY90 O43521
PDB IDs 1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P 3GEN 3K54 3OCS 3OCT 3P08 3PIX 3PIY 3PIZ 3PJ1 3PJ2 3PJ3 1F95 2K7W 2NL9 2V6Q 2VM6 2WH6 2YQ6 3D7V 3FDL 3IO8 3IO9 3KJ0 3KJ1 3KJ2 4B4S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
akt1  antipsychotic  atg  atg12  atg4b  atg5  atg7  autophagic  autophagosome  autophagosomes  autophagy  bak1  becn1  cdkn1a  cdkn1b  chloroquine  colocalization  dysfunctional  gabarap  henceforth  lc3b  map1lc3b  olanzapine  overtly  pmaip1  sqstm1  sy5y  trp53  unmask 
Tagcloud (Difference) ?
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
akt1  antipsychotic  atg  atg12  atg4b  atg5  atg7  autophagic  autophagosome  autophagosomes  autophagy  bak1  becn1  cdkn1a  cdkn1b  chloroquine  colocalization  dysfunctional  gabarap  henceforth  lc3b  map1lc3b  olanzapine  overtly  pmaip1  sqstm1  sy5y  trp53  unmask 
Tagcloud (Intersection) ?