ADAM17 and TNFRSF1A

  • Number of citations of the paper that reports this interaction (PMID 17010968)
  • 29
  • Data Source:
  • BioGRID (enzymatic study)

ADAM17

TNFRSF1A

Gene Name ADAM metallopeptidase domain 17 tumor necrosis factor receptor superfamily, member 1A
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
Protein-Protein Interactions 14 interactors: DLG1 ERBB4 FHL2 MAD2L1 MAD2L2 NOTCH1 PTPN3 SH3D19 TGFA TIMP3 TNF TNFRSF1A TNFRSF1B TNFSF11 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1
Entrez ID 6868 7132
HPRD ID 04703 01861
Ensembl ID ENSG00000151694 ENSG00000067182
Uniprot IDs B2RNB2 P78536 J9PH39 P19438
PDB IDs 1BKC 1ZXC 2A8H 2DDF 2FV5 2FV9 2I47 2M2F 2OI0 3B92 3CKI 3E8R 3EDZ 3EWJ 3G42 3KMC 3KME 3L0T 3L0V 3LE9 3LEA 3LGP 3O64 1EXT 1FT4 1ICH 1NCF 1TNR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anchored  apma  arguing  betacellulin  bzatp  cd23  cd62  chimeras  constitutive  convertase  cytoplasmic  disintegrin  dispensable  domain  ectodomain  influences  influx  ionomycin  metalloprotease  metalloproteinase  motif  negatively  pro  retention  shedding  tgfalpha  translationally  transmembrane 
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
Tagcloud (Difference) ?
anchored  apma  arguing  betacellulin  bzatp  cd23  cd62  chimeras  constitutive  convertase  cytoplasmic  disintegrin  dispensable  domain  ectodomain  influences  influx  ionomycin  metalloprotease  metalloproteinase  motif  negatively  pro  retention  shedding  tgfalpha  translationally  transmembrane 
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
Tagcloud (Intersection) ?