WIZ and TK1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		WIZ	TK1
Gene Name		widely interspaced zinc finger motifs	thymidine kinase 1, soluble
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Cytosol
	Molecular Function	Protein Binding Metal Ion Binding SET Domain Binding	Thymidine Kinase Activity ATP Binding Zinc Ion Binding Nucleoside Kinase Activity Identical Protein Binding
	Biological Process	Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization Protein Heterotrimerization	Liver Development Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Response To Toxic Substance Skeletal Muscle Cell Proliferation Phosphorylation Response To Nutrient Levels Pyrimidine Nucleoside Salvage Small Molecule Metabolic Process Thymidine Metabolic Process Response To Copper Ion Digestive Tract Development Protein Homotetramerization Response To Cortisol Nucleobase-containing Small Molecule Metabolic Process Fetal Process Involved In Parturition DNA Biosynthetic Process
Pathways			Pyrimidine salvage reactions Pyrimidine metabolism Metabolism of nucleotides
Drugs			Dithioerythritol Thymidine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions		14 interactors: C8orf33 CDKN1A EHMT1 EHMT2 OSGEP PIN1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	159 interactors: A1BG A2M AAMP ABHD4 ACTB ACTL6B ACTR1B ADAMTS10 ADD1 AGAP1 ALAS1 ALB APLP1 APP ARFGAP1 ASNA1 ATG16L2 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 C19orf60 CARHSP1 CCDC115 CCDC90B CDC20 CDK1 CDK4 CDKN1A CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE6 CPSF3L CRIP2 CRMP1 CSAD DACT1 DALRD3 DCAF13 DDAH2 DEAF1 DMPK DOCK7 DRAP1 DUS2 DYNC1I1 EEF1A1 EIF3G EIF4A2 EIF6 EXT2 EZH2 F13A1 FAF1 FAM20C FBN3 FGB FLAD1 FST FZR1 GAPDH GDF9 GDI1 GLB1 GPCPD1 HADHB HERC3 HMGXB3 HSPBAP1 IER3IP1 IGHM IMMT INPP5K ITSN1 JADE1 JMJD1C KDM6B KIF21B KIF5A KLHL23 KLHL5 KMT2B LOC148413 LRIF1 MAGEA4 MAST2 MED31 METTL23 MKI67 MPP1 MPPED1 MRFAP1 MRPL37 MSH2 NEUROD2 NGFR NKIRAS2 NMT2 NRBP1 ODC1 PAAF1 PDE4DIP PKM PLD3 PLXNA3 PPP4C PROC PSME1 PTPN4 PTPRK QARS RBBP4 RBM48 RPA1 RPL13 RPS2 RUVBL1 RXRA SDF4 SEMA5B SEPT6 SETDB1 SEZ6L2 SMC5 SNX1 SP110 SULT1A3 SUMO3 TAF1C TCTEX1D2 THOC3 TIAM2 TLE1 TMSB4X TP53 TRIM46 TRMT2A TSC2 TTC38 TUBA1A TUBB2A TUBB3 TYK2 UNC119 UPF2 USP4 WDR18 WDR60 WDR73 WIZ ZBTB16 ZNF431 ZXDC
Entrez ID		58525	7083
HPRD ID		11686	01771
Ensembl ID		ENSG00000011451	ENSG00000167900
Uniprot IDs		B3KVH1 M0QXA7 O95785	P04183
PDB IDs			1W4R 1XBT 2ORV 2WVJ
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Dimethylation Histone H3-K9 Methylation Histone H3-K9 Modification Histone Lysine Methylation Peptidyl-lysine Methylation Histone Methylation Protein Methylation Histone H3-K9 Dimethylation Peptidyl-lysine Modification Histone H3-K9 Trimethylation Histone H3-K27 Methylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Histone Modification Negative Regulation Of Circadian Rhythm Methylation Nitrogen Compound Metabolic Process Peptidyl-lysine Trimethylation Peptidyl-amino Acid Modification NcRNA Metabolic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Chromatin Organization DNA Methylation Fetal Process Involved In Parturition Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process DNA Modification Threonylcarbamoyladenosine Biosynthetic Process Skeletal Muscle Cell Proliferation Regulation Of Circadian Rhythm Regulation Of Mitotic Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Chromosome Organization Regulation Of Mitotic Nuclear Division Regulation Of Cell Cycle Process DNA Methylation On Cytosine Within A CG Sequence Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Digestive Tract Development Threonylcarbamoyladenosine Metabolic Process	Cellular Metabolic Process Regulation Of Protein Metabolic Process Cellular Protein Metabolic Process Developmental Process Anatomical Structure Development System Development Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organismal Development Cellular Localization Metabolic Process Regulation Of Metabolic Process Organelle Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Protein Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Catabolic Process RNA Metabolic Process Negative Regulation Of Cell Cycle Posttranscriptional Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Platelet Degranulation Gene Expression Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cellular Process Biosynthetic Process Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Cell Cycle Process Mitotic Cell Cycle Process Axon Guidance Chromatin Organization Viral Process Programmed Cell Death Negative Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Organic Substance Mitotic Cell Cycle Cellular Response To Growth Factor Stimulus
Tagcloud ?		ankyrin asd autism autistic ba21 ba40 boundaries brodmann delays dimethylation dorn ehmt1 ehmt2 g9a glp h3k9 heteromeric intellectual kleefstra lys968arg methyltransferases nonsynonymous novelty postmortem prioritized raphe restrictive surmise thr961ile	american artiodactyla assigned block blot cattle chr conservative conserved cow electrophoresis erbb2 hybrid hybridization localization localized means mink nf1 pepa pig prkca rara representatives sheep southern swine synteny umph2
Tagcloud (Difference) ?		ankyrin asd autism autistic ba21 ba40 boundaries brodmann delays dimethylation dorn ehmt1 ehmt2 g9a glp h3k9 heteromeric intellectual kleefstra lys968arg methyltransferases nonsynonymous novelty postmortem prioritized raphe restrictive surmise thr961ile	american artiodactyla assigned block blot cattle chr conservative conserved cow electrophoresis erbb2 hybrid hybridization localization localized means mink nf1 pepa pig prkca rara representatives sheep southern swine synteny umph2
Tagcloud (Intersection) ?