WIZ and OSGEP

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		WIZ	OSGEP
Description		WIZ zinc finger	O-sialoglycoprotein endopeptidase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Extracellular Exosome	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding Protein Binding Zinc Ion Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding	Protein Binding Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Metal Ion Binding TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization	TRNA Threonylcarbamoyladenosine Modification TRNA Modification TRNA Processing
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)	Food addiction ( 27106561)
Interacting Genes		17 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 PKNOX1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 LGALS4 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 WDR82 WIZ ZNF579 ZNF775
Entrez ID		58525	55644
HPRD ID		11686	10133
Ensembl ID		ENSG00000011451	ENSG00000092094
Uniprot IDs		A0A2R8YFV2 A0A669KAV7 A0A669KBG4 A0A669KBH9 M0QXA7 O95785	Q9NPF4
PDB IDs		8TZX 9DJT 9DJX	6GWJ
Enriched GO Terms of Interacting Partners?		Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Methyltransferase Activity Histone H3K9me2 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Peptidyl-lysine Dimethylation Histone H3K27 Methyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Methylation Nucleus Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei C2H2 Zinc Finger Domain Binding Peptidyl-lysine Methylation Epigenetic Regulation Of Gene Expression Protein-lysine N-methyltransferase Activity Cellular Response To Hypoxia Heterochromatin Formation Cellular Response To Decreased Oxygen Levels Nuclear Body Nucleoplasm Chromosome Cellular Response To Oxygen Levels Epigenetic Programming Of Gene Expression Protein Methylation DNA Methylation-dependent Constitutive Heterochromatin Formation Macromolecule Metabolic Process Cellular Response To Starvation Cis-trans Isomerase Activity Histone H3K56 Methyltransferase Activity Transcription Corepressor Binding Condensed Nuclear Chromosome Response To Starvation Constitutive Heterochromatin Formation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity RNA Metabolic Process Cellular Response To Nutrient Levels Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Nucleic Acid Metabolic Process ENoSc Complex DNA Synthesis Involved In Mitotic DNA Replication Phenotypic Switching P53 Binding Ethanolamine Transport Ethanolamine Transmembrane Transporter Activity
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