WIZ and RCC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		WIZ	RCC1
Description		WIZ zinc finger	regulator of chromosome condensation 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody Extracellular Exosome	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding Protein Binding Zinc Ion Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding	DNA Binding Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Membrane Reassembly Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Viral Process Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly
Pathways			Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)	Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		17 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 PKNOX1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CEBPA CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 LRIF1 NGFR NTMT1 NUDT21 NUP98 OGT PDHB PKM PTMA RAN RANBP1 RANBP3 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		58525	1104
HPRD ID		11686	01559
Ensembl ID		ENSG00000011451	ENSG00000180198
Uniprot IDs		A0A2R8YFV2 A0A669KAV7 A0A669KBG4 A0A669KBH9 M0QXA7 O95785	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs		8TZX 9DJT 9DJX	1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB 8UX1
Enriched GO Terms of Interacting Partners?		Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Methyltransferase Activity Histone H3K9me2 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Peptidyl-lysine Dimethylation Histone H3K27 Methyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Methylation Nucleus Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei C2H2 Zinc Finger Domain Binding Peptidyl-lysine Methylation Epigenetic Regulation Of Gene Expression Protein-lysine N-methyltransferase Activity Cellular Response To Hypoxia Heterochromatin Formation Cellular Response To Decreased Oxygen Levels Nuclear Body Nucleoplasm Chromosome Cellular Response To Oxygen Levels Epigenetic Programming Of Gene Expression Protein Methylation DNA Methylation-dependent Constitutive Heterochromatin Formation Macromolecule Metabolic Process Cellular Response To Starvation Cis-trans Isomerase Activity Histone H3K56 Methyltransferase Activity Transcription Corepressor Binding Condensed Nuclear Chromosome Response To Starvation Constitutive Heterochromatin Formation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity RNA Metabolic Process Cellular Response To Nutrient Levels Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Nucleic Acid Metabolic Process ENoSc Complex DNA Synthesis Involved In Mitotic DNA Replication Phenotypic Switching P53 Binding Ethanolamine Transport Ethanolamine Transmembrane Transporter Activity	Chromatin Organization Nucleoplasm Nucleus Chromatin Remodeling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Structural Constituent Of Chromatin Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleosome Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Kinetochore Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Protein Heterodimerization Activity Nuclear Transport Nucleocytoplasmic Transport Nuclear Pore Protein Export From Nucleus Ribosomal Large Subunit Export From Nucleus Chromosome Positive Regulation Of DNA Metabolic Process Ribosomal Small Subunit Export From Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of DNA Replication Cytosol Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Nuclear Envelope Ribosomal Subunit Export From Nucleus Extracellular Exosome Nuclear Export Nuclear Export Signal Receptor Activity Protein Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteolysis TORC1 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Biosynthetic Process Nuclear Retinoic Acid Receptor Binding Pyruvate Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus MRNA Cleavage And Polyadenylation Specificity Factor Complex
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