WIZ and RPS10

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		WIZ	RPS10
Gene Name		widely interspaced zinc finger motifs	ribosomal protein S10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Metal Ion Binding SET Domain Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization Protein Heterotrimerization	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: C8orf33 CDKN1A EHMT1 EHMT2 OSGEP PIN1 RCC1 RPP14 RPS10 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1	15 interactors: APP DMPK DNMT3B DVL3 EED FBXO25 HAP1 HIP1 KAT7 PFN2 PTTG1 SYK TCF25 WIZ XRCC6
Entrez ID		58525	6204
HPRD ID		11686	04697
Ensembl ID		ENSG00000011451	ENSG00000124614
Uniprot IDs		B3KVH1 M0QXA7 O95785	P46783
PDB IDs			3J3A
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Dimethylation Histone H3-K9 Methylation Histone H3-K9 Modification Histone Lysine Methylation Peptidyl-lysine Methylation Histone Methylation Protein Methylation Histone H3-K9 Dimethylation Peptidyl-lysine Modification Histone H3-K9 Trimethylation Histone H3-K27 Methylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Histone Modification Negative Regulation Of Circadian Rhythm Methylation Nitrogen Compound Metabolic Process Peptidyl-lysine Trimethylation Peptidyl-amino Acid Modification NcRNA Metabolic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Chromatin Organization DNA Methylation Fetal Process Involved In Parturition Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process DNA Modification Threonylcarbamoyladenosine Biosynthetic Process Skeletal Muscle Cell Proliferation Regulation Of Circadian Rhythm Regulation Of Mitotic Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Chromosome Organization Regulation Of Mitotic Nuclear Division Regulation Of Cell Cycle Process DNA Methylation On Cytosine Within A CG Sequence Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Digestive Tract Development Threonylcarbamoyladenosine Metabolic Process	Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Gene Expression Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Chromosome Organization Organelle Organization Gene Expression Regulation Of Vesicle-mediated Transport Positive Regulation Of Organelle Organization Regulation Of Exocytosis Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Protein Modification Process Genetic Imprinting Regulation Of Cell Differentiation Transcription, DNA-templated Positive Regulation Of Histone Methylation RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Catalytic Activity RNA Biosynthetic Process Positive Regulation Of Cell Cycle Process DNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Axon Cargo Transport Regulation Of Cellular Process Regulation Of Histone Methylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Cell Cycle Regulation Of Cellular Component Organization Regulation Of Neurogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Platelet Degranulation Positive Regulation Of JUN Kinase Activity Positive Regulation Of Histone Modification
Tagcloud ?		ankyrin asd autism autistic ba21 ba40 boundaries brodmann delays dimethylation dorn ehmt1 ehmt2 g9a glp h3k9 heteromeric intellectual kleefstra lys968arg methyltransferases nonsynonymous novelty postmortem prioritized raphe restrictive surmise thr961ile	26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps17 rps19 rps24 rps26 supports variations
Tagcloud (Difference) ?		ankyrin asd autism autistic ba21 ba40 boundaries brodmann delays dimethylation dorn ehmt1 ehmt2 g9a glp h3k9 heteromeric intellectual kleefstra lys968arg methyltransferases nonsynonymous novelty postmortem prioritized raphe restrictive surmise thr961ile	26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps17 rps19 rps24 rps26 supports variations
Tagcloud (Intersection) ?