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WIZ and SUV39H2
Number of citations of the paper that reports this interaction (PubMedID
23455924
)
0
Data Source:
BioGRID
(two hybrid)
WIZ
SUV39H2
Description
WIZ zinc finger
SUV39H2 histone lysine methyltransferase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Midbody
Extracellular Exosome
Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Corepressor Binding
Protein Binding
Zinc Ion Binding
Protein-containing Complex Binding
Metal Ion Binding
Histone Methyltransferase Binding
Transcription Cis-regulatory Region Binding
Protein Binding
Methyltransferase Activity
Zinc Ion Binding
Transferase Activity
Histone Methyltransferase Activity
Metal Ion Binding
Histone H3K9 Methyltransferase Activity
Histone H3 Methyltransferase Activity
Histone H3K9 Trimethyltransferase Activity
S-adenosyl-L-methionine Binding
Ubiquitin-like Ligase-substrate Adaptor Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Nuclear Cell Cycle DNA Replication
Protein Stabilization
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Chromatin Remodeling
Circadian Rhythm
Cell Differentiation
Methylation
Epigenetic Programming In The Zygotic Pronuclei
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of DNA-templated Transcription
Rhythmic Process
Cellular Response To Hypoxia
Pathways
PKMTs methylate histone lysines
Drugs
Diseases
GWAS
High light scatter reticulocyte percentage of red cells (
32888494
)
Monocyte percentage of white cells (
32888494
)
Response to cognitive-behavioural therapy in anxiety disorder (
31123309
)
Interacting Genes
17 interacting genes:
C8orf33
CDKN1A
CRBN
DOK5
EHMT1
EHMT2
OSGEP
PIN1
PKNOX1
RCC1
RPP14
RPS10
SMN1
SUV39H1
SUV39H2
TK1
TSC22D1
43 interacting genes:
AKAP9
APPL2
AR
BLZF1
C8orf74
CBX7
CDCA4
CEP70
CFAP100
CGGBP1
EWSR1
FAM20C
GOLGA6L9
GSTCD
H3C1
ID2
KCTD17
KLF3
KLHDC4
LCA5L
LNX1
LRIF1
MAGEA11
MCM3AP
MRFAP1
MTF2
MYL12A
NME4
ODAD3
PHF19
PNMA1
POLR3F
RAB3IP
RASSF1
SHC1
SMAD5
SNF8
UBE2V2
VHL
WIZ
ZNF212
ZNF557
ZNF57
Entrez ID
58525
79723
HPRD ID
11686
07580
Ensembl ID
ENSG00000011451
ENSG00000152455
Uniprot IDs
A0A2R8YFV2
A0A669KAV7
A0A669KBG4
A0A669KBH9
M0QXA7
O95785
Q9H5I1
PDB IDs
8TZX
9DJT
9DJX
2R3A
6P0R
Enriched GO Terms of Interacting Partners
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Histone H3K9 Methyltransferase Activity
Histone H3 Methyltransferase Activity
Histone Methyltransferase Activity
Histone H3K9me2 Methyltransferase Activity
Histone H3K9 Trimethyltransferase Activity
Peptidyl-lysine Dimethylation
Histone H3K27 Methyltransferase Activity
Negative Regulation Of Gene Expression, Epigenetic
Methyltransferase Activity
Methylation
Nucleus
Facultative Heterochromatin Formation
Epigenetic Programming In The Zygotic Pronuclei
C2H2 Zinc Finger Domain Binding
Peptidyl-lysine Methylation
Epigenetic Regulation Of Gene Expression
Protein-lysine N-methyltransferase Activity
Cellular Response To Hypoxia
Heterochromatin Formation
Cellular Response To Decreased Oxygen Levels
Nuclear Body
Nucleoplasm
Chromosome
Cellular Response To Oxygen Levels
Epigenetic Programming Of Gene Expression
Protein Methylation
DNA Methylation-dependent Constitutive Heterochromatin Formation
Macromolecule Metabolic Process
Cellular Response To Starvation
Cis-trans Isomerase Activity
Histone H3K56 Methyltransferase Activity
Transcription Corepressor Binding
Condensed Nuclear Chromosome
Response To Starvation
Constitutive Heterochromatin Formation
PCNA-p21 Complex
Negative Regulation Of Cardiac Muscle Tissue Regeneration
Thymidine Kinase Activity
TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity
RNA Metabolic Process
Cellular Response To Nutrient Levels
Protein Peptidyl-prolyl Isomerization
Phosphothreonine Residue Binding
Nucleic Acid Metabolic Process
ENoSc Complex
DNA Synthesis Involved In Mitotic DNA Replication
Phenotypic Switching
P53 Binding
Ethanolamine Transport
Ethanolamine Transmembrane Transporter Activity
Nucleoplasm
Protein Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Histone H3K36me3 Reader Activity
Nucleus
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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Tagcloud (Intersection)
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