PDCD6IP and CHMP4A

Number of citations of the paper that reports this interaction (PMID 12860994)
56

Data Source:
HPRD (in vitro, in vivo)

		PDCD6IP	CHMP4A
Gene Name		programmed cell death 6 interacting protein	charged multivesicular body protein 4A
Image
Gene Ontology Annotations	Cellular Component	Immunological Synapse Cytoplasm Microtubule Organizing Center Cytosol Focal Adhesion Membrane Vesicle Melanosome Extracellular Vesicular Exosome Endoplasmic Reticulum Exit Site	ESCRT III Complex Nucleus Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding SH3 Domain Binding Proteinase Activated Receptor Binding Protein Homodimerization Activity Calcium-dependent Protein Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Viral Life Cycle Viral Budding Via Host ESCRT Complex Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly	Cell Separation After Cytokinesis Posttranslational Protein Targeting To Membrane Membrane Budding Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Protein Homooligomerization Membrane Organization Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagic Vacuole Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion Uptake and actions of bacterial toxins HIV Infection Uptake and function of anthrax toxins Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		35 interactors: ARRDC1 ARRDC3 ATN1 CD2AP CEP55 CHMP4A CHMP4B CHMP4C CXCR1 EGFR F2R GRB2 HOXA1 ITSN1 ITSN2 KEAP1 MAPK6 PDCD6 PTK2B RAMP3 RNF11 SDCBP SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3RF1 SRC TAB1 TNIP2 TSG101 TTF2 VPS28 VPS37C YES1	12 interactors: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		10015	29082
HPRD ID		06425	16597
Ensembl ID		ENSG00000170248	ENSG00000254505
Uniprot IDs		C5MQH7 Q8WUM4	Q14D22 Q9BY43
PDB IDs		2OEV 2OEW 2OEX 2OJQ 2R02 2R03 2R05 2XS1 2XS8 2ZNE 3C3O 3C3Q 3C3R 3E1R 4JJY	3C3O
Enriched GO Terms of Interacting Partners?		Virion Assembly Locomotion Endocytosis Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Cell Migration Cell Separation After Cytokinesis Membrane Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Chemotaxis Viral Budding Transport Regulation Of Signal Transduction Viral Life Cycle Regulation Of Cellular Process Establishment Of Protein Localization Endosomal Transport Viral Protein Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Signal Transduction Viral Process Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of MAPK Cascade Neuron Projection Morphogenesis Regulation Of Intracellular Signal Transduction Cell Projection Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Organelle Organization Response To External Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Positive Regulation Of Metabolic Process Intracellular Transport Neuron Development Anatomical Structure Development Apoptotic Process Cell Morphogenesis Involved In Differentiation	Cell Separation After Cytokinesis Cell Division Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Metaphase Plate Congression Viral Life Cycle Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Centrosome Cycle Viral Process Vacuolar Transport Mitotic Sister Chromatid Segregation Endosomal Transport Sister Chromatid Segregation Regulation Of Cell Cycle Process Nucleus Organization Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Regulation Of Mitotic Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Viral Budding Regulation Of Spindle Assembly Regulation Of Microtubule-based Process Regulation Of Mitotic Spindle Organization Membrane Organization Chromosome Segregation Regulation Of Cell Cycle Regulation Of Cell Division Regulation Of Viral Release From Host Cell Virion Assembly Cell Cycle Process Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Establishment Of Organelle Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Organelle Localization Protein Transport Establishment Of Protein Localization Regulation Of Organelle Organization Regulation Of Cytoskeleton Organization Abscission Positive Regulation Of Viral Process Membrane Budding Negative Regulation Of Cytokinesis Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Localization In Cell
Tagcloud ?		129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Difference) ?		129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
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