PKN1 and HDAC5

  • Number of citations of the paper that reports this interaction (PMID 20188095)
  • 9
  • Data Source:
  • BioGRID (enzymatic study)

PKN1

HDAC5

Gene Name protein kinase N1 histone deacetylase 5
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bone mineral density (hip) ( 19801982)
  • Bone mineral density (spine) ( 19801982)
Protein-Protein Interactions 40 interactors: ACTN1 AKAP9 ARHGAP10 ARHGAP26 CASP3 CCDC85B CCNT2 CD44 CDC25C CDR2 CEP57L1 GOLGA2 HDAC5 HDAC6 HIST1H1A HIST2H3C HOMER3 KRT15 KRT31 MAP2K6 MAPK12 MAPT MARCKS MBP MID1 NEFH NEFL NEUROD2 PDPK1 PLD1 RHOA SPRR2D SSX2IP TNFRSF1B TRAF1 TRAF2 VIM WBSCR22 ZFAND6 ZNF282 59 interactors: ANKRA2 ANKRD11 ATF3 BCL6 BCOR BRMS1 CAMK1 CAMTA2 CBX5 CIITA CTBP1 DDX20 DYRK1B EEF1G ESR1 GABARAP GATA1 GATA2 GCM1 GNB1 HDAC3 HDAC7 HIF1A HOXC11 HR JDP2 KLF4 MAFF MEF2A MEF2C MEF2D NCOR1 NCOR2 NFATC1 NFKB2 NFKBIE NRIP1 PHB2 PKN1 PKN2 PRKAA1 PRKCD PRKD1 RFXANK RUNX3 SFN SIK1 SIK2 SIK3 SLC2A4RG SMAD3 SUV39H1 TAB2 UBC UBE2I YWHAB YWHAE YWHAQ ZBTB16
Entrez ID 5585 10014
HPRD ID 03019 09246
Ensembl ID ENSG00000123143 ENSG00000108840
Uniprot IDs Q16512 Q9UQL6
PDB IDs 1CXZ 1URF 2RMK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accordingly  androgen  ar  blocks  chip  colocalization  driver  enriched  epigenomic  establishing  facilitates  h3k4  h3k4me3  h3t11p  hyperexpressed  integrator  interacts  marked  mll  mll1  promoters  prostate  recruitment  seq  set1  severely  threonine  tri  wdr5 
125a  5p  activating  anticancer  apoptosis  converse  deacetylase  detailed  doi  downregulation  exist  hdaci  implications  induce  intrinsic  involving  loop  mediates  microrna  mir  mt  nevertheless  runx3  silenced  silencing  subsequently  transcriptionally  tumorigenesis 
Tagcloud (Difference) ?
accordingly  androgen  ar  blocks  chip  colocalization  driver  enriched  epigenomic  establishing  facilitates  h3k4  h3k4me3  h3t11p  hyperexpressed  integrator  interacts  marked  mll  mll1  promoters  prostate  recruitment  seq  set1  severely  threonine  tri  wdr5 
125a  5p  activating  anticancer  apoptosis  converse  deacetylase  detailed  doi  downregulation  exist  hdaci  implications  induce  intrinsic  involving  loop  mediates  microrna  mir  mt  nevertheless  runx3  silenced  silencing  subsequently  transcriptionally  tumorigenesis 
Tagcloud (Intersection) ?