HDAC5 and NCOR2

  • Number of citations of the paper that reports this interaction (PMID 10869435)
  • 138
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

HDAC5

NCOR2

Gene Name histone deacetylase 5 nuclear receptor corepressor 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bone mineral density (hip) ( 19801982)
  • Bone mineral density (spine) ( 19801982)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065)
  • Cognitive performance ( 19734545)
Protein-Protein Interactions 59 interactors: ANKRA2 ANKRD11 ATF3 BCL6 BCOR BRMS1 CAMK1 CAMTA2 CBX5 CIITA CTBP1 DDX20 DYRK1B EEF1G ESR1 GABARAP GATA1 GATA2 GCM1 GNB1 HDAC3 HDAC7 HIF1A HOXC11 HR JDP2 KLF4 MAFF MEF2A MEF2C MEF2D NCOR1 NCOR2 NFATC1 NFKB2 NFKBIE NRIP1 PHB2 PKN1 PKN2 PRKAA1 PRKCD PRKD1 RFXANK RUNX3 SFN SIK1 SIK2 SIK3 SLC2A4RG SMAD3 SUV39H1 TAB2 UBC UBE2I YWHAB YWHAE YWHAQ ZBTB16 84 interactors: AHR AKT1 AP2M1 AR ARNT ATXN1 ATXN1L BCL6 C1D CBFA2T2 CEBPB CEP63 CHUK CIR1 CNOT2 DDX20 E2F1 ESR1 ESR2 FOS FOXP1 HDAC1 HDAC10 HDAC3 HDAC4 HDAC5 HDAC7 HIST1H4A HNF4A INPP5K IRF5 JUN MYBL2 MYOD1 NCOA3 NCOA6 NCOR1 NFE2L2 NFKB1 NFKBIA NFKBIB NFKBIE NR1D1 NR1H2 NR1H4 NR1I2 NR2F1 NR2F2 NR3C1 NR4A1 PML POU2F1 PPARA PPARD PPARG RANBP9 RARA RARB RARG RBPJ RELA RUNX1 RUNX1T1 RXRA RXRG SAP30 SIN3A SKIL SNW1 SP1 SPEN SRF STAT5A STAT5B SUMO1 TBL1X THRA THRB TNIK TNIP2 UBE2I VDR YWHAE ZBTB16
Entrez ID 10014 9612
HPRD ID 09246 02910
Ensembl ID ENSG00000108840 ENSG00000196498
Uniprot IDs Q9UQL6 C9J0Q5 C9JE98 C9JFD3 Q9Y618
PDB IDs 1KKQ 1R2B 1XC5 2GPV 2L5G 2LTP 2ODD 3R29 3R2A 4A69
Enriched GO Terms of Interacting Partners?
Tagcloud ?
125a  5p  activating  anticancer  apoptosis  converse  deacetylase  detailed  doi  downregulation  exist  hdaci  implications  induce  intrinsic  involving  loop  mediates  microrna  mir  mt  nevertheless  runx3  silenced  silencing  subsequently  transcriptionally  tumorigenesis 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Difference) ?
125a  5p  activating  anticancer  apoptosis  converse  deacetylase  detailed  doi  downregulation  exist  hdaci  implications  induce  intrinsic  involving  loop  mediates  microrna  mir  mt  nevertheless  runx3  silenced  silencing  subsequently  transcriptionally  tumorigenesis 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Intersection) ?