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PRKAB2 and CSNK2B
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid, two hybrid)
PRKAB2
CSNK2B
Gene Name
protein kinase, AMP-activated, beta 2 non-catalytic subunit
casein kinase 2, beta polypeptide
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytosol
AMP-activated Protein Kinase Complex
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Protein Kinase CK2 Complex
PcG Protein Complex
Extracellular Vesicular Exosome
Molecular Function
AMP-activated Protein Kinase Activity
Protein Binding
Identical Protein Binding
Protein Serine/threonine Kinase Activity
Receptor Binding
Protein Binding
Transcription Factor Binding
Protein Kinase Regulator Activity
Protein Domain Specific Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Energy Reserve Metabolic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Carnitine Shuttle
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Fatty Acid Biosynthetic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Regulation Of Protein Kinase Activity
Membrane Organization
Mitotic Cell Cycle
Protein Phosphorylation
Signal Transduction
Axon Guidance
Negative Regulation Of Cell Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Wnt Signaling Pathway
Positive Regulation Of Activin Receptor Signaling Pathway
Adiponectin-activated Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Cellular Protein Complex Assembly
Regulation Of Protein Kinase Activity
Regulation Of DNA Binding
Endothelial Tube Morphogenesis
Pathways
Organelle biogenesis and maintenance
Integration of energy metabolism
Metabolism of lipids and lipoproteins
Regulation of Rheb GTPase activity by AMPK
IRS-mediated signalling
mTOR signalling
Translocation of GLUT4 to the plasma membrane
Import of palmitoyl-CoA into the mitochondrial matrix
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Fatty acid, triacylglycerol, and ketone body metabolism
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-related events
Mitochondrial biogenesis
IRS-mediated signalling
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
AMPK inhibits chREBP transcriptional activation activity
PKB-mediated events
PI3K Cascade
Mitotic Prometaphase
Signal transduction by L1
Axon guidance
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
L1CAM interactions
Signaling by Wnt
Cell Cycle, Mitotic
M Phase
WNT mediated activation of DVL
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by WNT in cancer
Condensation of Prometaphase Chromosomes
Drugs
Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions
70 interactors:
ADAMTSL4
BANP
BEND5
BLZF1
CALCOCO2
CASP6
CCDC33
CCDC36
CDX4
CREB3L1
CRX
CSNK2B
DAO
DDIT4L
DICER1
DST
EPM2A
FAM208B
FDX1
FLNC
GATA1
GATAD2B
GET4
GNB2L1
GOLGA2
GRN
IKZF1
IKZF3
KCTD5
KLF15
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LZTS2
MAGED1
MDFI
MEOX2
NEBL
PIAS2
PRDM14
PRKAA1
PRKAA2
PRKAG1
PRKAG2
PRKAG3
PSME3
PYGM
RBPMS
REL
RHEBL1
RIMBP3
SPRY2
STX11
STX19
TADA2A
TCF4
TP53BP2
TRAF2
TRIM10
UBXN11
YY1AP1
ZBTB32
175 interactors:
ABHD4
ACTB
ACTL6B
ACTR1B
ACTR5
ACVRL1
ADD1
ADH5
ADRBK1
ANGPT2
ANKRD28
AP2M1
APLP1
ARAF
ATF1
ATG101
ATXN3
BAG6
BCCIP
BID
BMI1
BRCA1
BTF3
C6orf136
C9orf114
CACNA1A
CALM1
CBX4
CCDC115
CCNH
CD163
CD81
CDC25B
CDC34
CDK1
CDK20
CDKN1A
CENPB
CHEK1
CHRNA4
CIC
COIL
COL4A2
COPS2
COPS3
COPS7A
CPNE7
CPSF3L
CSN1S1
CSN2
CSNK2A1
CSNK2A2
CTDP1
CTNNB1
DACT1
DALRD3
DENND5A
DNMT1
EIF2S2
EIF5
EIF6
EPS8
ERCC8
ESR1
FAF1
FBXL5
FGB
FGF1
FGF2
FIBP
FKBP3
FTH1
GADD45GIP1
GAMT
GBP2
GLB1
GNB5
HEXB
HIRIP3
HNRNPA2B1
HOXB6
HTRA1
IER3IP1
IRS1
ITSN1
JUN
KDM6B
KIF2C
LCK
LEPR
LMO4
LRP5L
LYN
LYST
MAPK14
MBD4
MGEA5
MME
MOXD1
MPP2
NAP1L1
NCF1
NMT2
NOLC1
NOTCH3
NRBP1
ODC1
PDS5A
PFKFB4
PHC2
PHF11
PHRF1
PIN1
PITPNA
PLXNA3
POT1
PPID
PPP3CC
PRKAB2
PRKCZ
PRNP
PROC
PTPRK
PYROXD2
RFC1
RNF126
RNF7
RPA1
RPL13
RPL41
RPL5
RPS6KA2
RPS6KA5
RPS6KB1
RPS6KB2
RRAD
RXRA
SARNP
SDHA
SEC11A
SHANK3
SHMT1
SHMT2
SIMC1
SIRT1
SNX2
SPSB3
SSB
STAT5A
STAU1
STK16
SUMO2
SYNE4
TCEAL7
TCTEX1D2
TLE1
TNFAIP1
TOP2B
TP53
TP53BP2
TSEN54
TUBB2B
UBE2I
UPF1
USO1
UTP14A
VDAC1
VRK3
WDR1
WDR18
WFIKKN1
ZNF44
ZNF71
ZNF784
ZNHIT1
Entrez ID
5565
1460
HPRD ID
04117
00278
Ensembl ID
ENSG00000131791
ENSG00000204435
Uniprot IDs
O43741
N0E4C7
P67870
Q5SRQ6
PDB IDs
2F15
2V8Q
2V92
2V9J
2Y8L
2Y8Q
2Y94
2YA3
4EAI
4EAJ
1DS5
1JWH
1QF8
3EED
4DGL
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle Arrest
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Glycogen Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Glycolytic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cell Cycle
Energy Reserve Metabolic Process
Regulation Of Cell Cycle
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Polysaccharide Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Organelle Organization
Gene Expression
Cell Cycle Process
Positive Regulation Of Phosphorylation
RNA Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Fatty Acid Biosynthetic Process
Cellular Process
Regulation Of Cellular Ketone Metabolic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Transcription From RNA Polymerase II Promoter
Regulation Of Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Binding
Regulation Of Metabolic Process
Regulation Of Carbohydrate Metabolic Process
Regulation Of Phosphorylation
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Cell Death
Cellular Metabolic Process
Response To Growth Factor
Regulation Of Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Developmental Process
Cellular Response To Organic Substance
Regulation Of Cellular Protein Metabolic Process
Cellular Protein Metabolic Process
Multicellular Organismal Development
Regulation Of Cell Proliferation
Anatomical Structure Development
Metabolic Process
Response To Organic Substance
Regulation Of Cellular Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell Cycle
Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
System Development
Response To Stress
Neurotrophin TRK Receptor Signaling Pathway
Response To Stimulus
Cell Cycle
Positive Regulation Of Protein Metabolic Process
Neurotrophin Signaling Pathway
Nitrogen Compound Metabolic Process
Biosynthetic Process
Cellular Protein Modification Process
Cellular Response To Stimulus
Cell Death
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
Death
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Radiation
Response To Radiation
Positive Regulation Of Cell Proliferation
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Cellular Response To Light Stimulus
Gene Expression
Regulation Of Phosphorylation
Peptidyl-amino Acid Modification
Programmed Cell Death
Cellular Aromatic Compound Metabolic Process
Tagcloud
?
bovine
casein
catalytic
cattle
chromosome
chromosomes
coast
composed
conserved
defined
east
encoding
fever
genomes
homology
hybrid
mapped
panel
parasitic
polymerase
rodent
segment
somatic
subunit
subunits
synteny
theileriosis
Tagcloud (Difference)
?
bovine
casein
catalytic
cattle
chromosome
chromosomes
coast
composed
conserved
defined
east
encoding
fever
genomes
homology
hybrid
mapped
panel
parasitic
polymerase
rodent
segment
somatic
subunit
subunits
synteny
theileriosis
Tagcloud (Intersection)
?